摘要
Abstract
Objective To analyze the clinical characteristics of pertussis in Beijing JingDu Children's Hospital from 2019 to 2024.Methods A retrospective analysis was conducted on 501 children with pertussis diagnosed at Beijing JingDu Children's Hospital from September 2019 to June 2024.The annual/monthly distribution,positive rate,average disease course before diagnosis,age distribution,gender distribution,and immunization status of the disease were statistically analyzed,and the clinical characteristics were summarized.Results In 2023,the number of confirmed cases of pertussis at Beijing JingDu Children's Hospital increased significantly,with a total of 133 confirmed cases,and the positive rate was 30.23%.From January to June 2024,a total of 350 cases were confirmed,with a positive rate of 18.68%.This disease had a high incidence in winter and spring(from November 2023 to April 2024),reaching its peak in January 2024.The positive rate fluctuated with the number of confirmed cases,showing a trend of first increasing and then decreasing,and it was the highest in December 2023(42.61%)and January 2024(34.64%).The average disease course before diagnosis was basically consistent with the increasing or decreasing trend of the number of confirmed cases.Among the diagnosed children,50.9%(255 cases)were aged≥7 years old,31.7%(159 cases)were aged 4-6 years old,and 17.4%(87 cases)were infants and toddlers.More than 95.0%of the children had completed the national immunization program.The clinical symptoms of 89.3%of the children were paroxysmal spasmodic cough.Laboratory tests showed that 9.0%of the children had the typical pertussis blood picture change of elevated peripheral blood lymphocytes.Conclusion In 2023,the incidence of pertussis is the highest at Beijing JingDu Children's Hospital.This disease is highly prevalent in winter and spring.Among the confirmed cases,school-age children account for a relatively high proportion.The average disease course before diagnosis is basically consistent with the increasing or decreasing trend of the number of confirmed cases.The main clinical manifestations of the children are typical paroxysmal spasmodic cough.Relevant departments should enhance cooperation,optimize prevention and control strategies,and safeguard children's health.关键词
儿童/百日咳/流行病学特征/临床特点Key words
Children/Pertussis/Epidemiological characteristics/Clinical characteristics分类
预防医学
