医学前沿（英文）Issue(2)：136-143,8.DOI:10.1002/med4.64O
Eosinophil count in cecal biopsies using artificial intelligence-based machine learning
Harsh C.Shah 1Anjali D.Amarapurkar1
作者信息
- 1. Department of Pathology,Lokmanya Tilak Municipal Medical College and Sion Hospital,Mumbai,India
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摘要
Abstract
Background:Tissue eosinophilia is a diagnostically challenging entity.An accurate diagnosis can benefit the patient with appropriate treatment.Histo-pathology is the gold standard.Manual counting results in errors and is time consuming.Artificial intelligence(AI)acts like a human brain in terms of memory and reproducibility.
Methods:The aim of this study was to determine the eosinophil count in gastrointestinal biopsies using AI and compare it with the manual method.A total of 400 digital images of hematoxylin and eosin-stained slides of gastro-intestinal biopsies were included in the study.Annotations were performed on images containing eosinophils.The neural network prepared using the Python language was a modified U-Net architecture containing five down blocks and five up blocks.The results obtained using the AI model were compared with manual counts.Pearson's correlation coefficient and Cohen's kappa coefficient of agreement were used for statistical analysis.
Results:Pearson's correlation coefficient demonstrated a strong positive correlation between AI and manual eosinophil(0.8),which suggests a very strong correlation.The Cohen's kappa coefficient of agreement was 0.85,which corresponds to excellent agreement.
Conclusions:The manual eosinophil count and AI predictions demonstrated a very strong positive correlation.It is necessary to count eosinophils using an AI model because it saves time,and eliminates interobserver variability and human error.关键词
artificial intelligence/eosinophilsKey words
artificial intelligence/eosinophils引用本文复制引用
Harsh C.Shah,Anjali D.Amarapurkar..Eosinophil count in cecal biopsies using artificial intelligence-based machine learning[J].医学前沿（英文）,2024,(2):136-143,8.
