针刺研究2025，Vol.50Issue(6)：728-734,7.DOI:10.13702/j.1000-0607.20240145
基于菌群-肠-脑轴的针刺作用机制研究进展
Research progress on the mechanism of acupuncture based on microbiota-gut-brain axis
摘要
Abstract
Microbiota-gut-brain axis refers to a bidirectional pathway between gut microbiota and the central nervous systems via neural,immune,endocrine and metabolic pathways,and its dysfunction is the crucial factor implicated in many diseases.Acupuncture adjusts the microbiota-gut-brain axis through regulating the structure and metabolic state of gut microbiota,improving the intestinal microenvironment,restoring the stability of intestinal mucosal barrier and blood-brain barrier,stimulating vagus nerve,reducing inflammation and modulating neurotransmitters,so that nervous system diseases,mental diseases,digestive system diseases and metabolic diseases can be treated.With the latest research trends and the cutting-edge technologies considered,the studies in the future should deepen the mechanism of acupuncture on the physiological pathway for modulating the structure and composition of gut microbiota as well as its holistic elaboration.关键词
针刺/电针/菌群-肠-脑轴/神经-免疫-内分泌Key words
Acupuncture/Electroacupuncture/Microbiota-gut-brain axis/Neuro-immuno-endocrine引用本文复制引用
邢敏,乔丽娜,万红叶,杨永升..基于菌群-肠-脑轴的针刺作用机制研究进展[J].针刺研究,2025,50(6):728-734,7.基金项目
中国中医科学院针灸研究所基本科研业务费自主选题创新人才专项(No.ZZ-YJ2023005) （No.ZZ-YJ2023005）
中国中医科学院科技创新工程重大攻关项目(No.CI2021A03301) （No.CI2021A03301）
