湖北医药学院学报2025，Vol.44Issue(3)：288-292,5.DOI:10.13819/j.issn.2096-708X.2025.03.006
原发性肺癌合并急性脑梗死临床特点分析
Clinical Characteristics of Primary Lung Cancer Patients Combined with Acute Cerebral Infarction
摘要
Abstract
Objective To analyze the clinical characteristics of primary lung cancer patients combined with acute cerebral infarction and to explore the risk factors for acute cerebral infarction in these patients and the characteristics of cranial mag-netic resonance imaging(MRI).Methods The clinical medical records of primary lung cancer patients admitted to the De-partment of Neurology and the Department of Oncology of Xiangyang No.1 People's Hospital from January 2019 to June 2024 were collected,including cases with or without acute cerebral infarction.Laboratory parameters of D-dimer,hemoglo-bin,leukocytes,platelets,glycated hemoglobin,and C-reactive protein,were collected,along with the information regard-ing comorbid conditions and cranial MRI.Results A total of 117 primary lung cancer patients were enrolled,with 59 in the study group(complicated with acute cerebral infarction)and 58 in the control group(not complicated).It was found that high D-dimer(OR=0.891,95%CI=0.807～0.985)and/orlowhemoglobin(OR=1.024,95%CI=1.003～1.046)were high-risk factors for acute cerebral infarction in primary lung cancer patients.MRI findings in patients with acute cerebral infarction primarily showed new infarct lesions with a pattern of multiple lesions.Conclusion High D-dimer and/or low he-moglobin in primary lung cancer patients are high-risk factors for acute cerebral infarction,while their cranial MRI primari-ly reflect a distribution of multiple new infarct lesions.关键词
急性脑梗死/原发性肺癌/临床特点/危险因素Key words
Acute cerebral infarction/Non-neurological primary malignancy/prognosis/Clinical characteristics/Risk factors引用本文复制引用
张军,刘倩,董佑红,杨军..原发性肺癌合并急性脑梗死临床特点分析[J].湖北医药学院学报,2025,44(3):288-292,5.基金项目
湖北省自然科学基金(2024AFD055,2022CFD117) （2024AFD055,2022CFD117）
襄阳市第一人民医院科技创新项目(XYY2025QN02) （XYY2025QN02）
