湖北医药学院学报2025，Vol.44Issue(3)：293-297,304,6.DOI:10.13819/j.issn.2096-708X.2025.03.007
高危儿神经心理发育的影响因素分析
Influencing Factors on the Neuropsychological Development of High-Risk Infants
摘要
Abstract
Objective To understand the neuropsychological development outcomes of high-risk infants and analyze the in-fluencing factors to provide scientific guidance for their management.Methods A bidirectional cohort study was conducted.High-risk infants who visited Taihe Hospital in Shiyan City from January 2022 to June 2024 were divided into the high-risk infant intervention group(n=137)and the high-risk infant control group(n=290)based on whether they received early intervention.A retrospective review of case data and longitudinal follow-up were conducted,with normal infants who re-ceived child health care at the same hospital during the same period selected as a control group(normal infant group,n=124).Neuropsychological development was monitored at 3,6,12,and 18 months of age,and binary logistic regression was used to analyze the influencing factors of developmental outcomes in high-risk infants.Results At 18 months,there was no difference in neuropsychological development between the high-risk infant intervention group and the normal infant group(P＞0.05),while a significant difference was observed between the high-risk infant control group and the normal in-fant group(P＜0.05).The rates of neurodevelopmental abnormalities were 14.6%in the high-risk infant intervention group,39.7%in the high-risk infant control group,and 4.0%in the normal infant group(P＜0.05).Risk factors for neu-rodevelopmental abnormalities in high-risk infants included maternal gestational diabetes(OR=2.642,95%CI=1.009～6.917,P=0.048),while a protective factor was early intervention(OR=0.326,95%CI=0.197～0.540,P＜0.001).Conclusion Child health care institutions should strengthen multidisciplinary collaboration,actively conduct screening and health education for gestational diabetes,and pay attention to the early intervention for high-risk infants.关键词
高危儿/神经心理发育/早期干预/影响因素Key words
High-risk infants/Neuropsychological development/Early intervention/Influencing factors引用本文复制引用
张启飞,江海宁,方向兰,于瀛均,罗程,罗清钦,席世兵,谢多双..高危儿神经心理发育的影响因素分析[J].湖北医药学院学报,2025,44(3):293-297,304,6.基金项目
湖北省自然科学基金青年项目(2021CFB270) （2021CFB270）
湖北医药学院附属太和医院院级项目(2022JJXM079) （2022JJXM079）
