中国实用儿科杂志2025，Vol.40Issue(5)：425-432,8.DOI:10.19538/j.ek2025050615
川崎病病因学研究进展
Research progress on the etiology of Kawasaki disease
顾昕雨 1龚方戚1
作者信息
- 1. 浙江大学医学院,浙江 杭州 310000
- 折叠
摘要
Abstract
Kawasaki disease(KD)is a systemic vasculitis that is more common in children under 5 years old.It can cause coronary artery lesions,and is the main cause of acquired heart disease in children.Early high-dose intravenous immunoglobulin(IVIG)combined with aspirin is currently the first-line treatment.Although Kawasaki disease has a history of more than 50 years since it was first reported and the incidence has been rising years after years,its specific etiology and pathogenesis still remain unclear,which is widely concerned by pediatricians in clinical practice.In order to understand KD better and provide ideas for its further diagnosis and treatment,this article discusses the current research status of KD etiology from the perspectives of infection,genetics and immunity.关键词
川崎病/病因学/感染因素/遗传易感性/免疫机制Key words
Kawasaki disease/etiology/infectious factors/genetic susceptibility/immune mechanism分类
临床医学引用本文复制引用
顾昕雨,龚方戚..川崎病病因学研究进展[J].中国实用儿科杂志,2025,40(5):425-432,8.
