局解手术学杂志2025，Vol.34Issue(6)：535-539,5.DOI:10.11659/jjssx.07E024119
罗哌卡因联合地佐辛在硬膜外麻醉初产妇无痛分娩中的应用
Application of ropivacaine combined with dezocine in painless delivery of primiparas with epidural anesthesia
摘要
Abstract
Objective To investigate the impacts of epidural anesthesia with ropivacaine combined with dezocine on lower limb motor nerve block and maternal and infant outcomes in primipara undergoing painless delivery.Methods A total of 159 primiparas who delivered in Nanjing Jiangbei Hospital were selected as the research objects,and divided into the blank group(53 cases),the ropivacaine group(53 cases)and the combined group(53 cases)by the random number table method.Parturients in the blank group were given natural delivery mode,parturients in the ropivacaine group were given ropivacaine epidural anesthesia,and parturients in the combined group were given dezocine anesthesia on the basis of ropivacaine.Analgesic effect at different time points,time of the first,second and third stage of labor,pressing times of analgesic pump,lower limbs motor nerve block,maternal and infant outcomes,and adverse reactions of parturients were compared among the three groups.Results At 10 minutes after analgesia,60 minutes after analgesia,when the cervix was fully dilated and when the fetus was delivered,the VAS scores of the parturients in the ropivacaine group and the combined group were lower than those in the blank group(P<0.05),and the VAS scores of the parturients in the combined group were significantly lower than those in the ropivacaine group(P<0.05).There was no significant difference in the time of the first,second or third stage of labor of parturients among the three groups(P>0.05);The pressing times of analgesic pump of parturients in the combined group was significantly less than that in the ropivacaine group(P<0.05).There was no statistically significant difference in terms of low limb motor nerve block after painless labor of parturients among the three groups(P>0.05).There were no statistically significant differences in the perineal incision rate or the Apgar scores of newborns at 1 minute and 5 minutes after birth among the three groups(P>0.05).The usage rate of forceps and the rate of conversion to cesarean section in the combined group were significantly lower than those in the ropivacaine group and the blank group(P<0.05).There was no statistically significant difference in the incidence of total adverse reactions among the blank group,the ropivacaine group and the combined group(P>0.05).Conclusion The combination of ropivacaine and dezocine for epidural anesthesia has a better analgesic effect on primiparas with painless delivery,has a smaller impact on lower limb motor nerve block in parturients,and can achieve better maternal and infant outcomes.关键词
无痛分娩/硬膜外麻醉/罗哌卡因/地佐辛/母婴结局Key words
painless delivery/epidural anesthesia/ropivacaine/dezocine/maternal and infant outcomes分类
医药卫生引用本文复制引用
杨栋栋,龚晓毅,凌云志,王亚祥,孙梅,段瑞,叶霞,张娅..罗哌卡因联合地佐辛在硬膜外麻醉初产妇无痛分娩中的应用[J].局解手术学杂志,2025,34(6):535-539,5.基金项目
安徽高校自然科学研究项目重点项目(KJ2021A0705) （KJ2021A0705）
