摘要
Abstract
Objective To explore the therapeutic effect of modified Xiaoyaowan combined with Fenmatong on menstrual disorders and its influence on the endometrial thickness of patients.Methods A total of 120 patients with menstrual disorders admitted to Liaoyang Central Hospital from June 2023 to June 2024 were selected as the research objects and divided into the Western medicine group and the traditional Chinese and Western medicine group by the random number table method,with 60 cases in each group.The Western medicine group was treated with oral Fenmatong,while the traditional Chinese and Western medicine group was treated with modified Xiaoyaowan on the basis of the treatment of the Western medicine group.The clinical efficacy,the endometrial thickness,endometrial blood flow parameters,related hormone levels and menstrual symptom scores before and after treatment of the two groups of patients were compared.Results The effective rate of treatment in the traditional Chinese and Western medicine group was 93.33%,which was higher than 78.33%in the Western medicine group(P＜0.05).Before treatment,there was no difference in endometrial thickness,resistance index(RI),peak systolic velocity of uterine arteries(PSV),and pulsatility index(PI)between the two groups(P＞0.05).After treatment,RI and PI decreased in both groups,with those in the traditional Chinese and Western medicine group being lower than those in the Western medicine group.Endometrial thickness and PSV increased in both groups,and those in the traditional Chinese and Western medicine group were higher than those in the Western medicine group.The differences were statistically significant(P＜0.05).Before treatment,there was no difference in luteinizing hormone,serum follicle-stimulating hormone and estradiol between the two groups(P＞0.05).After treatment,luteinizing hormone and follicle-stimulating hormone in both the traditional Chinese and Western medicine groups were higher than those in the Western medicine group,while estradiol was lower than that in the Western medicine group.The differences were statistically significant(P＜0.05).Before treatment,there was no difference in the scores of menstrual symptoms,COX Dysmenorrhea Symptom Scale(CMSS),and Menstrual blood loss chart(PBAC)between the two groups(P＞0.05).After the treatment,the scores of menstrual symptoms and CMSS in the traditional Chinese and Western medicine groups were lower than those in the Western medicine group,and the PBAC score was higher than that in the Western medicine group.The differences were statistically significant(P＜0.05).Conclusion The modified Xiaoyaowan combined with Fenmatong has a remarkable therapeutic effect on menstrual disorders.It can effectively improve the blood flow parameters of the endometrium in patients,regulate the thickness of the endometrium,optimize the sex hormone levels of patients,and relieve symptoms such as menstrual disorders,dysmenorrhea and abnormal menstrual flow.关键词
逍遥丸加减/芬吗通/月经失调/子宫内膜厚度/性激素/月经症状评分Key words
Modified Xiaoyaowan/Fenmatong/Menstrual disorders/Endometrial thickness/Sex hormones/Menstrual symptom score分类
临床医学
