中国医药科学2025，Vol.15Issue(9)：73-76,94,5.DOI:10.20116/j.issn2095-0616.2025.09.17
2型糖尿病患者血浆致动脉硬化指数与周围神经病变的相关性研究
Research on the correlation between atherogenic index of plasma and peripheral neuropathy in patients with type 2 diabetes mellitus
摘要
Abstract
Objective To investigate the correlation between atherogenic index of plasma(AIP)and diabetic peripheral neuropathy(DPN)in patients with type 2 diabetes mellitus(T2DM),and to evaluate its predictive value for DPN.Methods A total of 90 patients with T2DM admitted to Hongqi Hospital Affiliated to Mudanjiang Medical University from September 2022 to December 2023 were collected and divided into the DPN group(n=62)and the non DPN group(n=28).All patients underwent electromyography.Results With the increase of AIP level,the proportion of DPN increased obviously(P<0.05).The motor conduction velocity of bilateral common peroneal nerve and sensory conduction velocity(SCV)of bilateral posterior tibial nerve and superficial peroneal nerve decreased gradually(P<0.05).Binary logistic regression analysis showed that AIP(OR=2.826,P<0.001)was still an independent risk factor for DPN after adjusting for the course of diabetes mellitus,glycosylated hemoglobin,triglyceride,total cholesterol and low-density lipoprotein.ROC curve analysis showed that the area under the curve predicted by AIP was 0.791,the sensitivity was 92.90%and the specificity was 51.60%.Conclusion High AIP is an independent risk factor for DPN.关键词
血浆致动脉硬化指数/2型糖尿病/糖尿病周围神经病变/血脂异常Key words
Atherogenic index of plasma/Type 2 diabetes mellitus/Diabetic peripheral neuropathy/Dyslipidemia分类
医药卫生引用本文复制引用
刘艳,郭长秀,安云凤,王信,王德平..2型糖尿病患者血浆致动脉硬化指数与周围神经病变的相关性研究[J].中国医药科学,2025,15(9):73-76,94,5.基金项目
黑龙江省牡丹江市应用技术研究与开发计划项目(HT2022NS071) （HT2022NS071）
黑龙江省省属高等学校基本科研业务费科研项目(2020-KYYWF-0762). （2020-KYYWF-0762）
