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Network pharmacology approach to unveiling the mechanism of berberine in the amelioration of morphine tolerance

HAN Shuai Du Zhikang WANG Zirui HUANG Tianfeng GE Yali SHI Jianwen GAO Ju

中医杂志(英文版)2025,Vol.45Issue(2):376-384,9.
中医杂志(英文版)2025,Vol.45Issue(2):376-384,9.DOI:10.19852/j.cnki.jtcm.2025.02.012

Network pharmacology approach to unveiling the mechanism of berberine in the amelioration of morphine tolerance

Network pharmacology approach to unveiling the mechanism of berberine in the amelioration of morphine tolerance

HAN Shuai 1Du Zhikang 2WANG Zirui 2HUANG Tianfeng 3GE Yali 3SHI Jianwen 4GAO Ju3

作者信息

  • 1. Institute of Translational Medicine,Medical College,Yangzhou University,Yangzhou 225009,China||Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases,Yangzhou University,Yangzhou 225009,China||Northern Jiangsu People's Hospital Affiliated to Yangzhou University,Yangzhou 225009,China
  • 2. Institute of Translational Medicine,Medical College,Yangzhou University,Yangzhou 225009,China||Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases,Yangzhou University,Yangzhou 225009,China
  • 3. Northern Jiangsu People's Hospital Affiliated to Yangzhou University,Yangzhou 225009,China
  • 4. Peking University People's Hospital,Qingdao 266111,China||Women and Children's Hospital,Qingdao University,Qingdao 266034,China
  • 折叠

摘要

关键词

microglia/berberine/network pharmacology/NF-kappa B/morphine tolerance/Huanglian decoction

Key words

microglia/berberine/network pharmacology/NF-kappa B/morphine tolerance/Huanglian decoction

引用本文复制引用

HAN Shuai,Du Zhikang,WANG Zirui,HUANG Tianfeng,GE Yali,SHI Jianwen,GAO Ju..Network pharmacology approach to unveiling the mechanism of berberine in the amelioration of morphine tolerance[J].中医杂志(英文版),2025,45(2):376-384,9.

基金项目

Supported by Natural Science Foundation-funded Project:Study on the Mechanism of Mechanical Stress Sensing Element Piezo Type Mechanosensitive Ion Channel Component 2 Interacting with Nuclear Receptor Subfamily 4 Group A Member 2 Mediating Traumatic Brain Injury(No.82172190) (No.82172190)

中医杂志(英文版)

0255-2922

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