首页|期刊导航|中医杂志（英文版）|Integrating network pharmacology and experimental validation to uncover the synergistic effects of Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)with 5-fluorouracil in colorectal cancer models

Integrating network pharmacology and experimental validation to uncover the synergistic effects of Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)with 5-fluorouracil in colorectal cancer models

TAN Xiying GU Ruxin TAO Jing ZHANG Yu SUN Ruiqian YIN Gang ZHANG Shuo TANG Decai

中医杂志（英文版）2025，Vol.45Issue(2)：385-398,14.

中医杂志（英文版）2025，Vol.45Issue(2)：385-398,14.DOI:10.19852/j.cnki.jtcm.2025.02.004

Integrating network pharmacology and experimental validation to uncover the synergistic effects of Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)with 5-fluorouracil in colorectal cancer models

TAN Xiying ¹GU Ruxin ²TAO Jing ³ZHANG Yu ⁴SUN Ruiqian ⁵YIN Gang ⁵ZHANG Shuo ⁶TANG Decai⁵

作者信息

1. Department of Pharmacy,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China
2. Department of Pain Management,Affiliated Drum Tower Hospital,Medical School of Nanjing University,Nanjing 210008,China||School of Pharmacy,Nanjing Medical University,Nanjing 211166,China
3. School of Basic Medicine and Clinical Pharmacy,China Pharmaceutical University,Nanjing 210009,China
4. School of Pharmacy,Nanjing Medical University,Nanjing 211166,China
5. School of Integrated Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China
6. Department of Pharmacy,Nantong Hospital of Traditional Chinese Medicine,Nantong,226001,China
折叠

摘要

关键词

fluorouracil/parasitic sensitivity tests/colorectal neoplasms/network pharmacology/Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)

Key words

fluorouracil/parasitic sensitivity tests/colorectal neoplasms/network pharmacology/Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)

引用本文复制引用

TAN Xiying,GU Ruxin,TAO Jing,ZHANG Yu,SUN Ruiqian,YIN Gang,ZHANG Shuo,TANG Decai..Integrating network pharmacology and experimental validation to uncover the synergistic effects of Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)with 5-fluorouracil in colorectal cancer models[J].中医杂志（英文版）,2025,45(2):385-398,14.

基金项目

Supported by National Natural Science Foundation of China Youth Found Project:Anti-Colorectal Cancer Metastasis Mechanism of Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)According to the Hypoxia-Inducible Factor 2 Alpha/β-Catenin Cross-Talk Which Influence the Colon Tumor Stem Cells in Hypoxia Microenvironment(No.82003961) （Radix Astragali Mongolici）

National Natural Science Foundation of China Youth Found Project:the Mechanism of the Compatibility of Huangqi(Radix Astragali Mongolici)and Ezhu(Rhizoma Curcumae Phaeocaulis)on the Early Metastasis of Hepatocellular Carcinoma Mediated by Cancer Associated Fibroblasts(82104408) （Radix Astragali Mongolici）

Science Foundation of China Project:Involvement of Hypoxia Inducible Factor-1α Signal in Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)Combination Induced Remolding of Tumor Hypoxic Microenvironment(No.82074035) （Radix Astragali Mongolici）

and Science and Technology Development Project of Traditional Chinese Medicine in Jiangsu Province:Mechanism of Huangqi(Radix Astragali Mongolici)-Ezhu(Rhizoma Curcumae Phaeocaulis)Herb Pair on the Inhibition of Colon Cancer Metastasis Through the Wnt/β-catenin Pathway(No.YB201921) （Radix Astragali Mongolici）

中医杂志（英文版）

ISSN：0255-2922

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