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Hypolipidemic effect and mechanism of Hedan tablet(荷丹片)based on network pharmacology

HU Huiming WENG Jiajun TANG Fangrui WANG Yaqi FAN Shengxian WANG Xuecheng CUI Can SHAO Feng ZHU Yanchen

中医杂志(英文版)2025,Vol.45Issue(2):408-421,14.
中医杂志(英文版)2025,Vol.45Issue(2):408-421,14.DOI:10.19852/j.cnki.jtcm.2025.02.015

Hypolipidemic effect and mechanism of Hedan tablet(荷丹片)based on network pharmacology

Hypolipidemic effect and mechanism of Hedan tablet(荷丹片)based on network pharmacology

HU Huiming 1WENG Jiajun 2TANG Fangrui 3WANG Yaqi 3FAN Shengxian 3WANG Xuecheng 3CUI Can 4SHAO Feng 3ZHU Yanchen5

作者信息

  • 1. College of pharmacy,Nanchang Medical College & Key Laboratory of Pharmacodynamics and Safety Evaluation,Health Commission of Jiangxi Province & Key Laboratory of Pharmacodynamics and Quality Evaluation on anti-Inflammatory Chinese Herbs,Jiangxi Administration of Traditional Chinese Medicine,Nanchang 330052,China
  • 2. Peking University Traditional Chinese Medicine Clinical Medical School(Xiyuan),Beijing 100191,China
  • 3. Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Jiangxi University of Chinese Medicine,Nanchang 330004,China
  • 4. College of pharmacy,Nanchang Medical College,Nanchang,Jiangxi 330052,China
  • 5. College of Computer Science,Jiangxi University of Chinese Medicine,Nanchang 330004,China
  • 折叠

摘要

关键词

hyperlipidemia/mechanism/network pharmacology/ultra-performance liquid chromatography-quadrupole-time-of-flight-tandem mass spectrometry/Hedan tablet

Key words

hyperlipidemia/mechanism/network pharmacology/ultra-performance liquid chromatography-quadrupole-time-of-flight-tandem mass spectrometry/Hedan tablet

引用本文复制引用

HU Huiming,WENG Jiajun,TANG Fangrui,WANG Yaqi,FAN Shengxian,WANG Xuecheng,CUI Can,SHAO Feng,ZHU Yanchen..Hypolipidemic effect and mechanism of Hedan tablet(荷丹片)based on network pharmacology[J].中医杂志(英文版),2025,45(2):408-421,14.

基金项目

Supported by the National Natural Science Foundation of China:Effects of Hawthorn Leaves Flavonoids on Atherosclerosis Unstable Plaques based on the Mechanism of Liver-gut axis Liver X Receptor(LXR-a)-mediated Iron and Lipid Metabolism Disorders(No.82260794),the Natural Science Foundation of Jiangxi Province:based on Secreted Phospholipase A2 Type ⅡA(sPLA2-ⅡA)Regulating Lipid Mediated Foam Cell Formation to Explore the Effect and Molecular Mechanism of Hawthorn Leaf Flavonoids on Anti-atherosclerosis(No.20212BAB206013),the Key R&D Program of Jiangxi Province:Research on the Quality Enhancement and Industrialization Technology Improvement of the Lipid-Lowering Traditional Chinese Medicine"Hedan Tablet"(No.20201BBG71005),Science and Technology Project of Jiangxi Provincial Department of Education:based on the"Phlegm-Stasis"Theory to Explore the Effects and Molecular Mechanisms of Hawthorn Leaves Flavonoids on Improving Iron and Lipid Metabolism Disorders in Atherosclerosis(No.GJJ2203502) (LXR-a)

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