针灸推拿医学（英文版）2025，Vol.23Issue(3)：264-270,7.DOI:10.1007/s11726-025-1509-x
针药并用治疗抗结核药物引起的腹泻临床观察
Clinical observation on the combined use of acupuncture and medication in the treatment of diarrhea induced by anti-tuberculosis drugs
摘要
Abstract
Objective:To observe the clinical efficacy of acupuncture at the front-Mu points and the lower He-sea points combined with Western medication in the treatment of diarrhea induced by anti-tuberculosis drugs,as well as the effects on clinical symptoms and serum albumin. Methods:Seventy patients with diarrhea caused by anti-tuberculosis drugs were divided into an observation group and a control group according to the different treatment methods,with 35 cases in each group.Both groups were treated with the same Western medication,and the observation group was additionally treated with acupuncture at the front-Mu points and the lower He-sea points.After treatment,changes in the Hart score,traditional Chinese medicine(TCM)symptom score,and serum albumin were observed in both groups. Results:There was no statistically significant difference in the Hart score,TCM symptom score,and serum albumin level between the two groups before treatment(P>0.05).No adverse reactions occurred during treatment in either group.After 3 d of treatment,the total effective rate of the observation group was 68.6%,which was higher than 25.7%of the control group(P<0.01);after 7 d of treatment,the total effective rate of both the observation group and the control group was 100.0%,but the cured rate of the observation group was 80.0%,which was significantly higher than 2.9%of the control group(P<0.01).The Hart score and TCM symptom score of both groups after 3 d and 7 d of treatment were significantly lower than those before treatment(P<0.05),and the scores of the observation group were lower than those of the control group(P<0.05).After 7 d of treatment,the albumin level of the observation group was significantly higher than that of the control group(P<0.05). Conclusion:The addition of acupuncture at the front-Mu points combined with lower He-sea points to routine Western mediation treatment for diarrhea induced by anti-tuberculosis drugs is more effective than Western medication alone and can improve the clinical symptoms and nutritional status of the patients at an early stage.关键词
针刺疗法/针药并用/穴,募/穴,下合/募合配穴法/腹泻/抗结核药物/药物相关的副作用和不良反应Key words
Acupuncture Therapy/Acupuncture Medication Combined/Points,Front-Mu/Points,Lower He-sea/Front-Mu and He-sea Points Combination/Diarrhea/Anti-tuberculosis Drug/Drug-Related Side Effects and Adverse Reactions分类
医药卫生引用本文复制引用
俞珊,李志明,杨荔慧,何珂,王涛..针药并用治疗抗结核药物引起的腹泻临床观察[J].针灸推拿医学（英文版）,2025,23(3):264-270,7.基金项目
This study was supported by National Key Science and Technology Research and Development Program Project of the"13th Five-Year Plan"(国家科技重大专项"十三五"项目,No.2018ZX10725509_001). （国家科技重大专项"十三五"项目,No.2018ZX10725509_001）
