神经药理学报2025，Vol.15Issue(1)：14-18,5.DOI:10.3969/j.issn.2095-1396.2025.01.003
骨髓细胞形态学异常与血清铁蛋白水平在骨髓增生异常综合征患者中的相关性分析
Correlation Analysis Between Bone Marrow Cell Morphological Abnormalities and Serum Ferritin Levels in Patients with Myelodysplastic Syndrome
瞿啸鹏 1张园 2葛炎玲 2张洪波1
作者信息
- 1. 江苏省南通市通州区人民医院检验科,南通,226300,中国
- 2. 江苏省南通市通州区人民医院血液净化中心,南通,226300,中国
- 折叠
摘要
Abstract
Objective:To investigate the correlation between bone marrow cell morphological abnormalities and serum ferritin levels in patients with myelodysplastic syndrome,providing reference for clinical diagnosis and prognostic evaluation.Methods:100 MDS patients admitted to Nantong Tongzhou District People's Hospital from January 2021 to December 2023 were selected as research subjects.Bone marrow cell morphological characteristics were observed using an Olympus CX31 microscope,routine blood parameters were detected using a Mindray BC7500 blood cell analyzer,and serum ferritin levels were measured by electrochemiluminescence immunoassay.Data analysis was performed using SPSS 25.0 statistical software.Results:A significant positive correlation was found between the percentage of bone marrow blast cells and serum ferritin levels(r=0.642,P<0.01);the proportion of ring sideroblasts also showed a significant positive correlation with serum ferritin levels(r=0.583,P<0.01).Patients with severe bone marrow morphological abnormalities had significantly higher serum ferritin levels compared to those with mild to moderate abnormalities(P<0.05).Conclusion:The degree of bone marrow cell morphological abnormalities is closely correlated with serum ferritin levels in MDS patients.Combined detection has important clinical value in evaluating disease progression.关键词
骨髓增生异常综合征/骨髓细胞形态学/血清铁蛋白/相关性分析Key words
myelodysplastic syndrome/bone marrow cell morphology/serum ferritin/correlation analysis分类
药学引用本文复制引用
瞿啸鹏,张园,葛炎玲,张洪波..骨髓细胞形态学异常与血清铁蛋白水平在骨髓增生异常综合征患者中的相关性分析[J].神经药理学报,2025,15(1):14-18,5.
