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外泌体在靶向药物递送与疾病治疗中的应用与机制研究

要祎冉 张健东 李炜

神经药理学报2025,Vol.15Issue(1):55-64,10.
神经药理学报2025,Vol.15Issue(1):55-64,10.DOI:10.3969/j.issn.2095-1396.2025.01.009

外泌体在靶向药物递送与疾病治疗中的应用与机制研究

Application and Mechanism Study of Exosomes in Targeted Drug Delivery and Disease Therapy

要祎冉 1张健东 1李炜2

作者信息

  • 1. 河北北方学院药学院,张家口,075000,中国
  • 2. 河北北方学院药学院,张家口,075000,中国||河北省神经损伤与修复重点实验室,承德,067000,中国
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摘要

Abstract

As endogenous nanovesicles,exosomes promote cellular communication and exchange by transporting intracellular proteins,nucleic acids and lipids,and are ideal drug delivery vehicles due to their good biocompatibility,high stability and specific targeting to tissues and cells.In addition,the application mechanism of exosomes in the diagnosis and treatment of neurological diseases,tumors,and cardiovascular diseases has also been thoroughly studied.In this paper,we reviewed the application of exosomes in targeted drug delivery and the mechanism study of exosomes in the treatment of diseases,aiming to provide theoretical guidance for future research and clinical application.

关键词

外泌体/药物载体/靶向治疗

Key words

exosomes/drug carriers/targeted therapy

分类

药学

引用本文复制引用

要祎冉,张健东,李炜..外泌体在靶向药物递送与疾病治疗中的应用与机制研究[J].神经药理学报,2025,15(1):55-64,10.

基金项目

河北省神经损伤与修复重点实验室开放课题(No.NJKF202402),河北北方学院面上项目(No.XJ2024021) (No.NJKF202402)

神经药理学报

2095-1396

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