Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect:a multistage metabolomic profiling and Mendelian randomization study
Mengyuan Wang Kaifeng Pan Wenqing Li Zhouyi Yin Hengmin Xu Zongchao Liu Sha Huang Wenhui Wu Yang Zhang Tong Zhou Weicheng You
Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect:a multistage metabolomic profiling and Mendelian randomization study
Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect:a multistage metabolomic profiling and Mendelian randomization study
摘要
关键词
Gastric cancer/plasma metabolites/Mendelian randomization/L-aspartic acidKey words
Gastric cancer/plasma metabolites/Mendelian randomization/L-aspartic acid引用本文复制引用
Mengyuan Wang,Kaifeng Pan,Wenqing Li,Zhouyi Yin,Hengmin Xu,Zongchao Liu,Sha Huang,Wenhui Wu,Yang Zhang,Tong Zhou,Weicheng You..Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect:a multistage metabolomic profiling and Mendelian randomization study[J].癌症生物学与医学(英文版),2025,22(5):525-538,14.基金项目
This study was funded by the National Natural Science Foundation of China(No.82273704),Noncommunicable Chronic Diseases-National Science and Technology Major Project(No.2023ZD0501400-2023ZD0501402),Beijing Hospitals Authority's Ascent Plan(DFL20241102),Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support(No.ZLRK202325),China Postdoctoral Science Foundation(2024M760152),Peking University Medicine Fund for World's Leading Discipline or Discipline Cluster Development(No.BMU2022XKQ004),and Science Foundation of Peking University Cancer Hospital(Nos.BJCH2024BJ02,XKFZ2410,BJCH2025CZ04,and 2022-27). (No.82273704)