北京大学学报（医学版）2025，Vol.57Issue(3)：436-441,6.DOI:10.19723/j.issn.1671-167X.2025.03.005
基于RE-AIM框架儿童青少年近视与肥胖共病综合干预实施性研究结局指标的构建
Establishment of outcome indicators for the implementation of comprehensive inter-vention for multimorbidity of myopia and obesity among children and adolescents based on the RE-AIM framework
摘要
Abstract
Objective:To develop outcome indicators for the implementation of comprehensive inter-ventions targeting the multimorbidity of myopia and obesity in children and adolescents,providing a basis for the co-prevention of multimorbidity and the outcome measurement of implementation research in children and adolescents.Methods:Based on the RE-AIM framework,a preliminary set of indicators was constructed.The Delphi method was employed,with experts scoring and providing feedback on the proposed indicators via questionnaires.After each round of consultation,expert enthusiasm index,authority coefficient,coordination degree,and consensus level were calculated.Expert opinions were col-lected and analyzed to modify,delete,or add indicators based on consultation results and screening crite-ria.Two Delphi rounds were conducted until consensus was achieved.Results:A total of 28 experts par-ticipated actually in both rounds.The Kendall's W coefficients for the two rounds of expert consultation were0.352(x2=413.952,P＜0.001)and 0.499(x2=405.044,P＜0.001),both statistically sig-nificant.The final outcome indicators for implementation research on comprehensive interventions for myopia and obesity comorbidity in children and adolescents included five primary dimensions with 13 secondary and 20 tertiary indicators.The dimension of reach included the number of children and adoles-cents involved,participant representativeness,and full-course participation representativeness.The di-mension of effectiveness included multimorbidity incidence,myopia incidence,spherical equivalent,body mass index(BMI),overweight and obesity prevalence,waist-to-height ratio,comprehensive health knowledge score,and comprehensive health behavior score.The dimension of adoption covered school representativeness and representativeness of school nurses and teachers involved in implementation.The dimension of implementation included fidelity,content modification,and cost.The dimension of mainte-nance included individual health outcomes and organizational sustainment.Conclusion:This study developed implementation outcome indicators for comprehensive interventions targeting multimorbidity of myopia and obesity among the children and adolescents based on the RE-AIM framework.These indica-tors can serve as a reference for optimizing intervention research strategies related to common multimor-bidity among children and adolescents in China.关键词
近视/肥胖/儿童青少年/RE-AIM框架/德尔菲法Key words
Myopia/Obesity/Child and adolescent/RE-AIM framework/Delphi method分类
医药卫生引用本文复制引用
张依航,蔡珊,陈子玥,刘云飞,党佳佳,师嫡,李佳欣,黄天彧,宋逸..基于RE-AIM框架儿童青少年近视与肥胖共病综合干预实施性研究结局指标的构建[J].北京大学学报（医学版）,2025,57(3):436-441,6.基金项目
首都卫生发展科研专项重点攻关项目(2022-1G-4251)Supported by Capital's Funds for Health Improvement and Research(2022-1G-4251) （2022-1G-4251）
