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突触可塑性的调节机制及其与神经系统疾病关系的研究进展

汪临华 霍颖倩 李婷婷 刘晏民 席娅琳 王美玲

国际医药卫生导报2025,Vol.31Issue(12):1968-1971,4.
国际医药卫生导报2025,Vol.31Issue(12):1968-1971,4.DOI:10.3760/cma.j.cn441417-20240926-12007

突触可塑性的调节机制及其与神经系统疾病关系的研究进展

Research progress on regulation mechanisms of synaptic plasticity and its relationship with nervous system diseases

汪临华 1霍颖倩 1李婷婷 1刘晏民 1席娅琳 2王美玲1

作者信息

  • 1. 滨州医学院附属医院神经内科,滨州 256600
  • 2. 遂宁市中心医院神经内科,遂宁 629000
  • 折叠

摘要

Abstract

The regulatory mechanisms of synaptic plasticity are complex and diverse,and are closely related to many diseases of the nervous system.Impaired synaptic plasticity is found in many neurodegenerative and demyelinating diseases.What is synaptic plasticity?Which factors regulate synaptic plasticity?Can we slow down the progression of the diseases and improve the prognosis regulating synaptic plasticity?In this review,we summarize the regulatory mechanisms of synaptic plasticity and its relationship with nervous system diseases,and explore new therapeutic targets and possible mechanisms for treatment.

关键词

突触可塑性/小胶质细胞/氧化应激/神经炎症/进展

Key words

Synaptic plasticity/Microglia/Oxidative stress/Neuroinflammation/Progress

引用本文复制引用

汪临华,霍颖倩,李婷婷,刘晏民,席娅琳,王美玲..突触可塑性的调节机制及其与神经系统疾病关系的研究进展[J].国际医药卫生导报,2025,31(12):1968-1971,4.

基金项目

山东省医药卫生科技发展计划(2018WS539) Plan of Medical and Health Science and Technology Development in Shandong Province(2018WS539) (2018WS539)

国际医药卫生导报

1007-1245

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