日用化学品科学2025，Vol.48Issue(6)：7-16,10.DOI:10.3969/j.issn.1006-7264.2025.06.002
莱菔子提取物的美白及抗衰老功效研究
Study on the whitening and anti-aging efficacy of Raphanus sativus extract
陈秦君 1李国庆2
作者信息
- 1. 云南白药集团上海科技有限公司,上海 201107
- 2. 云南白药集团有限公司,云南 昆明 650500
- 折叠
摘要
Abstract
The whitening and anti-aging efficacy of different solvent extracts of Raphanus sativus was investigated.Results showed that the extract of Raphanus sativus(ethyl acetate layer)had a significant inhibitory effect on the synthesis of melanin in B16 cells,while it did not have a significant inhibitory effect on tyrosinase activity in B16 cells.It had a certain antioxidant effect,but it did not have a significant effect on the secretion of hyaluronic acid in fibroblasts.It had a significant promotional effect on type I collagen secretion with some inhibitory effect on elastin secretion in fibroblasts.The extract of Raphanus sativus(petroleum ether layer)had a certain inhibitory effect on melanin synthesis in B16 cells,a significant inhibitory effect on tyrosinase activity in B16 cells,a weak antioxidant effect,and a certain promotional effect on hyaluronic acid expression in fibroblasts.In contrast,it had no significant effect on type I collagen and elastin.Raphanus sativus extract(aqueous layer)had a certain inhibitory effect on melanin synthesis in B16 cells at high concentrations,a certain inhibitory effect on tyrosinase activity in B16 cells at low concentrations,whereas a weak antioxidant effect,a certain promotional effect on hyaluronic acid expression in fibroblasts,a certain promotional effec t on elastin expression,a certain promotional effect on elastin expression,a certain promotion effect on the expression of elastin and no obvious effect on type I collagen at medium concentration.关键词
莱菔子/美白/黑色素/抗氧化性/抗衰老Key words
Raphanus sativus/whitening/melanin/antioxidant property/anti-aging分类
化学工程引用本文复制引用
陈秦君,李国庆..莱菔子提取物的美白及抗衰老功效研究[J].日用化学品科学,2025,48(6):7-16,10.
