食管疾病2025,Vol.7Issue(2):119-122,134,5.DOI:10.15926/j.cnki.issn2096-7381.2025.02.008
NLRP3炎性小体在常见食管疾病中的作用机制及研究进展
The Mechanisms and Research Progress of NLRP3 Inflammasome in Common Esophageal Diseases
摘要
Abstract
Inflammasomes have received extensive attention in recent years,among which NLRP3 is the most representative inflammasome,which plays an important role in a variety of diseases,including esophageal diseases.The mechanism of NLRP3 inflammasome in common esophageal diseases,including esophageal cancer,esophagitis and esophageal stricture,has not been systematically sorted out,and this review summarizes the role of NLRP3 inflammasome and its mediated signaling pathway mechanism in common esophageal diseases,as well as the corresponding treatment methods,which will provide new strategies for clinical treatment.关键词
NLRP3/食管疾病/炎性小体/药物治疗/信号通路Key words
NLRP3/esophageal diseases/inflammasomes/drug therapy/signaling pathway分类
临床医学引用本文复制引用
张一凡,石林林,杨海军,姚香怡,高社干..NLRP3炎性小体在常见食管疾病中的作用机制及研究进展[J].食管疾病,2025,7(2):119-122,134,5.基金项目
河南省中原英才计划(育才系列)河南省医学科技攻关省部共建重点项目(SBGJ202102199)洛阳市社会发展公益专项医疗卫生重点项目(2302016A) (育才系列)