心脑血管病防治2025，Vol.25Issue(5)：41-45,53,6.DOI:10.3969/j.issn.1009-816x.2025.05.009
左束支区域起搏在心力衰竭心脏再同步化治疗中的优势及面临的挑战
The advantages and challenges of left bundle branch area pacing in cardiac resynchronization therapy for heart failure
摘要
Abstract
Biventricular pacing cardiac resynchronization therapy(BVP-CRT)is considered the primary treatment for patients with heart failure combined with reduced left ventricular ejection fraction(LVEF)and electro-mechanical dyssynchrony of the heart.However,part of patients receiving BVP-CRT do not respond to the treatment.Left bundle branch area pacing(LBBaP)is a new method emerging in recent years,which can improve the electrical activity and pumping function of the heart by stimulating the left bundle branch region.Multiple studies have shown that LBBaP is superior to BVP.It can provide CRT with a narrower QRS duration,and it leads to greater improvements in LVEF and cardiac function.However,LBBaP is not suitable for all heart failure patients who require CRT,and its success rate in heart failure patients is limited due to myocardial fibrosis,nonspecific intraventricular conduction delay,and right atrium or right ventricle enlargement.This article reviews the advantages and challenges of LBBaP in CRT treatment of heart failure.关键词
左束支区域起搏/心脏再同步化治疗/传导系统起搏/心力衰竭Key words
Left bundle branch area pacing/Cardiac resynchronization therapy/Conduction system pacing/Heart failure引用本文复制引用
唐念,陈晓晓,李鸿飞,郎明健,张登洪..左束支区域起搏在心力衰竭心脏再同步化治疗中的优势及面临的挑战[J].心脑血管病防治,2025,25(5):41-45,53,6.基金项目
成都市医学科研课题立项项目(2023219) （2023219）
