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Single-cell transcriptomics reveals the cellular dynamics of hexafluoropropylene oxide dimer acid in exerting mouse male reproductive toxicity

Xupeng Zang Yongzhong Wang Lei Jiang Yuhao Qiu Yue Ding Shengchen Gu Gengyuan Cai Ting Gu Linjun Hong

畜牧与生物技术杂志（英文版）2025，Vol.16Issue(3)：1073-1091,19.

畜牧与生物技术杂志（英文版）2025，Vol.16Issue(3)：1073-1091,19.DOI:10.1186/s40104-025-01177-x

Single-cell transcriptomics reveals the cellular dynamics of hexafluoropropylene oxide dimer acid in exerting mouse male reproductive toxicity

Xupeng Zang ¹Yongzhong Wang ¹Lei Jiang ¹Yuhao Qiu ¹Yue Ding ¹Shengchen Gu ¹Gengyuan Cai ²Ting Gu ¹Linjun Hong³

作者信息

1. State Key Laboratory of Swine and Poultry Breeding Industry,National Engineering Research Center for Breeding Swine Industry,Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding,College of Animal Science,South China Agricultural University,Guangzhou 510642,China
2. State Key Laboratory of Swine and Poultry Breeding Industry,National Engineering Research Center for Breeding Swine Industry,Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding,College of Animal Science,South China Agricultural University,Guangzhou 510642,China||Yunfu Subcenter of Guangdong Laboratory for Lingnan Modern Agriculture,Yunfu 527300,China
3. State Key Laboratory of Swine and Poultry Breeding Industry,National Engineering Research Center for Breeding Swine Industry,Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding,College of Animal Science,South China Agricultural University,Guangzhou 510642,China||National Regional Gene Bank of Livestock and Poultry(Gene Bank of Guangdong Livestock and Poultry),Guangzhou 510642,China
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摘要

关键词

Cellular dynamics/GenX/Reproductive toxicity/Single-cell RNA sequencing/Testis

Key words

Cellular dynamics/GenX/Reproductive toxicity/Single-cell RNA sequencing/Testis

引用本文复制引用

Xupeng Zang,Yongzhong Wang,Lei Jiang,Yuhao Qiu,Yue Ding,Shengchen Gu,Gengyuan Cai,Ting Gu,Linjun Hong..Single-cell transcriptomics reveals the cellular dynamics of hexafluoropropylene oxide dimer acid in exerting mouse male reproductive toxicity[J].畜牧与生物技术杂志（英文版）,2025,16(3):1073-1091,19.

基金项目

This work was supported by the Guangdong Provincial Key Area Research and Development Program[grant number 2022B0202090002]and China Postdoc-toral Science Foundation[grant number 2024M760977]. （）

畜牧与生物技术杂志（英文版）

ISSN：1674-9782

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