摘要
Abstract
The extracellular matrix(ECM),a pericellular network composed of various proteins,polysaccharides,and other components,is essential for maintaining the function of normal tissues and organs.Abnormal deposition and modification of ECM may lead to pathological conditions,such as the occurrence and progression of fibrosis and tumors.As a novel non-invasive parameter for quantifying ECM,the extracellular volume fraction(ECV)can reflect the microenvironment of tumors and evaluate the degree of tissue fibrosis.It holds significant clinical value for clinicians in assessing the severity of abdominal organ fibrosis,predicting the differentiation of abdominal tumor tissues,differentiating tumor types,and evaluating treatment efficacy.This article reviewed the measurement of CT-ECV and its applications in abdominal diseases,aiming to provide new technologies and perspectives for the diagnosis and treatment of abdominal diseases and improve the level of clinical management.关键词
细胞外基质/细胞外体积分数/计算机断层扫描/双能量CT/腹部疾病/组织纤维化/腹部肿瘤Key words
extracellular matrix/extracellular volume fraction/computed tomography/dual-energy CT/abdominal diseases/tissue fibrosis/abdominal tumor分类
医药卫生
