现代畜牧科技Issue(6)：25-27,3.DOI:10.19369/j.cnki.2095-9737.2025.06.007
新流腺三联灭活疫苗对腺病毒流行毒株的保护性研究
Study on the Protective Effect of the Triple Inactivated Vaccine Against the Epidemic Strains of Adenovirus
孙彦军 1丛海生 1肖燕 1贺笋 1曹剑 1王华荣 1郑学功 1刘强德 1高扬毅 1周洋 1张晓明 1吴钰宸1
作者信息
- 1. 天康制药股份有限公司,江苏 苏州 215000
- 折叠
摘要
Abstract
Fowl adenovirus disease(FAdV),also known as Ankara virus,is an acute and highly lethal infectious disease caused by serotype 4 of group I adenovirus.This disease occurs in broilers,laying hens and Sanhuang chickens,and chickens of different ages can be infected.It has a high mortality rate and a fast transmission speed.In order to verify the immunoprotective effect of the combined inactivated vaccines against Newcastle disease,avian influenza(subtype H9)and fowl adenovirus disease(group I serotype 4)produced by different manufacturers on the prevalent strains of fowl adenovirus disease(group I serotype 4),healthy and susceptible specific-pathogen-free(SPF)chickens aged 21 to 28 days were immunized with the combined inactivated vaccines for poultry.After immunization,the chickens were continuously observed for 21 days,and all the immunized groups showed good spirit and appetite.At 21 days after immunization,the chickens were challenged with the prevalent strain SD70 of fowl adenovirus(group I serotype 4).All the immunized groups were 100%protected,while all the chickens in the control group were 100%infected and 90%of them died.The test results show that the combined inactivated vaccines for chickens produced by different manufacturers have good immunoprotective effects and can resist the attack of the prevalent strain SD70 of adenovirus.关键词
SPF鸡/灭活疫苗/免疫Key words
SPF Chicken/inactivated vaccine/immune分类
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孙彦军,丛海生,肖燕,贺笋,曹剑,王华荣,郑学功,刘强德,高扬毅,周洋,张晓明,吴钰宸..新流腺三联灭活疫苗对腺病毒流行毒株的保护性研究[J].现代畜牧科技,2025,(6):25-27,3.
