中国临床医学影像杂志2025,Vol.36Issue(6):385-388,392,5.DOI:10.12117/jccmi.2025.06.002
sMRI、fMRI及dMRI影像特征与感音神经性耳聋患者小脑功能的关系
The relationship between sMRI,fMRI and dMRI imaging features and cerebellar functions in patients with sensorineural hearing loss
摘要
Abstract
Objective:This study aims to explore the relationship between sMRI,fMRI and dMRI imaging features and cerebellar functions in patients with sensorineural hearing loss.Methods:This prospective study was conducted from April 2023 to April 2024 and included 72 patients with sensorineural hearing loss and 36 volunteers who underwent health check-ups as the control group.All subjects were scanned using conventional sequence,DTI,and BOLD sequence.The study compared sMRI brain gray matter results,dMRI brain white matter results,and fMRI results between the study and control groups,as well as among patients with different cerebellar functions.We also investigated the relationship between sMRI,fMRI,dMRI imaging characteristics and cerebellar functions in patients with sensorineural hearing loss.Results:In the research and cerebellar ataxia groups,the FA,AD and RD values in specific brain regions(right temporal fusiform,right middle occipital gyrus,right cerebral peduncle,right thalamic radiation,right posterior limb of internal capsule,right corticospinal tract,right external capsule,genu,splenium,and body of the corpus callosum)were lower than in the control and normal cerebellar functions groups.The voxel size,MNI-X,MNI-Y,and MNI-Z values in other regions(right inferior temporal gyrus,left inferior temporal gyrus,left straight gyrus of frontal lobe,left hippocampus of temporal lobe,right superior temporal gyrus)were significantly higher in the research and cerebellar ataxia groups than in the control and normal cerebellar functions groups(P<0.05).Cerebellar ataxia showed negative correlations with sMRI and dMRI indicators but positive correlations with fMRI indicators.Conclusion:sMRI was able to show structural changes in the cerebellum,fMRI revealed patterns of functional activation in the cerebellum during auditory tasks,and dMRI assessed changes in the cerebellum's functional connections by detecting the integrity of its connections with other brain areas.关键词
听力损失,感音神经性/磁共振成像Key words
Hearing Loss,Sensorineural/Magnetic Resonance Imaging分类
医药卫生引用本文复制引用
邹科,谭宋雯,朱淑贤,杨博文,阿布都韦力·阿不都西库尔,邱娅..sMRI、fMRI及dMRI影像特征与感音神经性耳聋患者小脑功能的关系[J].中国临床医学影像杂志,2025,36(6):385-388,392,5.基金项目
新疆维吾尔自治区科学技术厅项目(编号:2022D01C11). (编号:2022D01C11)