中国临床医学2025，Vol.32Issue(3)：362-368,7.DOI:10.12025/j.issn.1008-6358.2025.20250174
经食管内镜纵隔良性肿瘤切除术的可行性和安全性分析
Feasibility and safety of transesophageal endoscopic resection for benign mediastinal tumors
摘要
Abstract
Objective To explore the feasibility,safety,and efficacy of transesophageal endoscopic surgery for mediastinal tumors.Methods A retrospective analysis was conducted on the clinical data of 17 patients who underwent transesophageal endoscopic resection for benign mediastinal tumors at the Endoscopy Center of Zhongshan Hospital,Fudan University,between January 1,2016 and December 31,2024.Epidemiological characteristics,surgical parameters,adverse events,and follow-up outcomes were analyzed.Results Among the 17 patients,there were 9 males and 8 females,with an average age of(42.4±14.5)years and an average tumor size of(2.6±1.6)cm.Pathological types included esophageal duplication cysts(6 cases,35.3%),bronchogenic cysts(5 cases,29.4%),gastroenteric cysts(3 cases,17.6%),schwannomas(2 cases,11.8%),and lymphangioma(1 case,5.9%).Fourteen patients(82.4%)underwent submucosal tunneling endoscopic resection(STER),3 patients(17.6%)underwent natural orifice transluminal endoscopic mediastinal surgery.All surgeries were successfully completed without conversion to open surgery.En bloc resection was achieved in 11 patients(64.7%),with an average operative time of(60.9±32.6)min.No intraoperative bleeding or mucosal injury occurred,and 4 patients(23.5%)experienced minor complications(pneumothorax,fever,recurrent laryngeal nerve injury),all of which resolved with conservative treatment.The average postoperative hospital stay was(3.2±1.5)days,and no recurrence was observed during the follow-up period.Conclusions Transesophageal endoscopic resection of benign mediastinal tumors is a safe,effective,and minimally invasive treatment method.Further validation of its efficacy and safety through large-scale prospective studies is warranted.关键词
纵隔良性肿瘤/内镜纵隔良性肿瘤切除术/内镜治疗/新技术Key words
benign mediastinal tumor/endoscopic resection for benign mediastinal tumors/endotherapy/new technique分类
医药卫生引用本文复制引用
于佳,马丽芸,苏伟,林生力,李全林,周平红,郜娉婷..经食管内镜纵隔良性肿瘤切除术的可行性和安全性分析[J].中国临床医学,2025,32(3):362-368,7.基金项目
上海市东方英才计划青年项目(QNKJ2024006).Supported by Shanghai Oriental Talent Program Youth Project(QNKJ2024006). （QNKJ2024006）
