不同血清型鸭疫里默氏杆菌对SPF鸡的致病性OA
The Pathogenicity of Riemerella anatipestifer with Different Serotypes to SPF Chickens
鸭疫里默氏杆菌(Riemerella anatipestifer,RA)主要感染雏鸭,而目前感染鸡的相关研究较少.为了解RA对鸡的致病性,选取5个血清型的RA纯净菌株,采用腿肌注射方法接种21日龄SPF鸡,观察其临床症状和脏器病变情况.结果显示:血清2型、6型、7型RA均对SPF鸡有较强的致病性,导致鸡出现精神沉郁、羽毛粗乱、趴窝甚至死亡等临床症状,尸体剖检发现明显的心包炎、肝周炎病变,且能在病变组织中重新分离到相应菌株.结果表明,鸭源RA对SPF鸡有较强的致病性.本研究对RA的鸡群传播风险作出了预警,为RA感染的防控提供了参考.
Riemerella anatipestifer(RA)mainly infects ducklings,while there are few studies on relevant infection in chickens.In order to identify the pathogenicity of RA to chickens,pure RA strains of 5 serotypes were selected and injected intramuscularly into 21-day-old specific pathogen free(SPF)chickens to observe their clinical symptoms and organ lesions.The results showed that RA serotypes 2,6 and 7 were strongly pathogenic to SPF chickens,leading to clinical symptoms such as lethargy,ruffled feathers,recumbency,and even death.Obvious pericarditis and perihepatic lesions were observed through post-mortem examination,and corresponding strains could be re-isolated in the lesions.In conclusion,RA derived of ducks was strongly pathogenic to SPF chickens.Early warning of the risk of RA transmission in chicken flocks was issued,providing a reference for future prevention and control of the disease.
黄冬;刘思佳;王睿智;邵钰;卜德新;张伯顺;迟丽丽;于春梅;丛雁方
青岛蔚蓝生物股份有限公司,山东 青岛 266100||甘肃农业大学,甘肃 兰州 730070青岛蔚蓝生物股份有限公司,山东 青岛 266100青岛蔚蓝生物股份有限公司,山东 青岛 266100甘肃农业大学,甘肃 兰州 730070青岛蔚蓝生物股份有限公司,山东 青岛 266100青岛蔚蓝生物股份有限公司,山东 青岛 266100青岛蔚蓝生物股份有限公司,山东 青岛 266100青岛蔚蓝生物股份有限公司,山东 青岛 266100青岛蔚蓝生物股份有限公司,山东 青岛 266100
畜牧业
鸭疫里默氏杆菌SPF鸡致病性
RASPF chickenpathogenicity
《中国动物检疫》 2025 (6)
113-116,4
甘肃省优秀博士生资助项目(23JRRA1445)
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