中国卒中杂志2025，Vol.20Issue(5)：566-580,15.DOI:10.3969/j.issn.1673-5765.2025.05.005
中国卒中疾病负担与经济负担的整合分析
An Integrated Analysis of Disease Burden and Economic Burden of Stroke in China
摘要
Abstract
Objective To conduct an integrated analysis of the disease burden and economic burden of various types of stroke in China. Methods Based on published literature and public databases,including data from the 2013 national epidemiological survey of stroke in China,the annual report on cardiovascular health and diseases in China,the China health statistical yearbook,and the 2021 GBD study,a comprehensive analysis was conducted on the indicators reflecting the disease burden and economic burden of various types of stroke in China,such as the incidence,death,prevalence,DALYs,number of discharged patients,average hospitalization cost per visit,and the total hospitalization cost for patients with stroke. Results(1)Current situation:from 2021 to 2022,the surveillance of cardiovascular and cerebrovascular events among Chinese residents revealed that the age-standardized incidence rate of stroke among individuals aged 18 and above in China was 338.6/100 000.According to the China health statistical yearbook,the crude death rate of stroke among urban residents in China in 2021 was 140.02/100 000,accounting for 21.71%of total urban deaths.Among rural residents,the crude death rate of stroke was 175.58/100 000,representing 23.62%of total rural deaths.The 2021 GBD study indicated that the age-standardized prevalence rate of stroke in China in 2021 was 1301.4/100 000,with ischemic stroke at 1018.8/100 000,intracerebral hemorrhage at 222.1/100 000,subarachnoid hemorrhage at 68.9/100 000,and the age-standardized DALYs rate for stroke was 2648.0/100 000.(2)Trends:the 2021 GBD study showed that compared to 1990,the age-standardized incidence rate of stroke decreased by 9.8%,the age-standardized death rate decreased by 43.0%,the age-standardized prevalence rate increased by 11.5%,and the age-standardized DALYs rate decreased by 45.2%.The age-standardized incidence and prevalence rates of ischemic stroke continued to exhibit an upward trend.In contrast,the downward trends in the age-standardized death rate and DALYs rate were not statistically significant.Further gender-specific analysis indicated that the age-standardized death rate and DALYs rate of ischemic stroke in females showed a statistically significant downward trend,while the corresponding trend in males was not statistically significant.(3)Economic burden:in 2020,the total hospitalization cost of ischemic stroke in China amounted to 74.77 billion yuan,and for intracerebral hemorrhage reached 30.91 billion yuan.The average hospitalization cost per visit was 9824.9 yuan for ischemic stroke and 20 397.6 yuan for intracerebral hemorrhage,respectively.After excluding the effects of price fluctuations,since 2004,the average annual growth rates of total hospitalization costs for ischemic stroke and intracerebral hemorrhage were 16.8%and 12.8%,respectively.Meanwhile,the average annual growth rates of the average hospitalization cost per visit were 1.1%and 4.4%,respectively. Conclusions From 1990 to 2021,the age-standardized incidence rate,age-standardized death rate,and DALYs rate of stroke in China exhibited a downward trend.However,the age-standardized incidence and prevalence rates of ischemic stroke continued to exhibit an upward trend.From 2004 to 2020,the average hospitalization cost per visit for ischemic stroke and intracerebral hemorrhage in China increased substantially.With the rapid process of population aging in China,the future disease burden and economic burden attributable to stroke will continue to rise.关键词
卒中/疾病负担/发病率/死亡率/患病率/伤残调整生命年/经济负担Key words
Stroke/Disease burden/Incidence rate/Death rate/Prevalence rate/Disability-adjusted life year/Economic burden分类
医药卫生引用本文复制引用
翟屹,杨帆,李天琪,谢瑀婷,刘改芬..中国卒中疾病负担与经济负担的整合分析[J].中国卒中杂志,2025,20(5):566-580,15.基金项目
四大慢病重大专项(2023ZD0503600,2023ZD0503605) （2023ZD0503600,2023ZD0503605）
