内科2025，Vol.20Issue(2)：169-172,4.DOI:10.16121/j.cnki.cn45-1347/r.2025.02.09
健康体检人群幽门螺杆菌感染与代谢指标的相关性
Correlations between Helicobacter pylori infection and metabolic indicators in a healthy physical examination population
摘要
Abstract
Objective To investigate the correlations between Helicobacter pylori(H.pylori)infection and metabolic indicators such as blood lipids and uric acid(UA)in a healthy physical examination population.Methods A total of 1,093 healthy individuals undergoing physical examinations were enrolled as research subjects and divided into an H.pylori-positive group or an H.pylori-negative group according to the H.pylori infection.General data(e.g.,sex,age)and levels of total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),α-L-fucosidase(AFU),total bilirubin(T-BiL),total bile acid(TBA),UA,and blood urea nitrogen(BUN)were compared between the two groups;logistic regression analysis was used to identify risk factors for H.pylori infection.Results Among the 1,093 healthy individuals undergoing physical examinations,258 were H.pylori-positive,showing an infection rate of 23.60%.The H.pylori-positive group had a higher proportion of females,greater age,and elevated levels of TC and LDL-C compared with the H.pylori-negative group(all P<0.05).No statistically significant difference was observed in BMI or level of UA,BUN,TG,AFU,T-BiL,or TBA between the two groups(all P>0.05).Logistic regression analysis identified age and gender as independent risk factors for H.pylori infection(all P<0.05).Conclusion H.pylori infection is correlated with gender and age.While H.pylori infection influences lipid metabolism,it has no effect on UA,T-BiL,or TBA metabolism.关键词
幽门螺杆菌/血脂/尿酸/总胆红素/总胆汁酸Key words
Helicobacter pylori/Blood lipids/Uric acid/Total bilirubin/Total bile acid分类
临床医学引用本文复制引用
秦娇莉,石清清,丁燕平,朱俞蓓,李卫..健康体检人群幽门螺杆菌感染与代谢指标的相关性[J].内科,2025,20(2):169-172,4.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(Z-A20230092) （Z-A20230092）
