生物资源2025，Vol.47Issue(3)：222-233,12.DOI:10.14188/j.ajsh.20250103001
钩藤质量标准历史沿革与质控技术研究进展
Research progress on the historical evolution of quality standards and quality control technologies of Uncariae Ramulus Cum Uncis
摘要
Abstract
Uncariae Ramulus Cum Uncis(URCU)is a typical multi-source traditional Chinese medicine,and its quality evaluation is an important step to ensure its clinical efficacy and safety.We systematically analyze the current situa-tion of quality standards and processing specifications of URCU domestically and internationally,and review the research progress in quality control technology of URCU in recent years.This study seeks to establish evidence-based strategies for enhancing the quality standards of URCU and advancing quality control technology for multi-source traditional Chinese medicines.At present,the identification of the authenticity of URCU to verify botanical origin is primarily conducted through three approaches:macroscopic characteristics,microscopy,and thin-layer chromatography.The impurities and active ingredients are controlled through the determination of moisture content,ash content,extractives.The basic pro-cessing steps for URCU decoction pieces in various provinces and cities include cleaning,cutting,and drying,and the quality control indicators of the decoction pieces are basically the same as those of raw medicinal materials.The problems that urgently need to be solved in the quality control of URCU are quality variations among multiple sources and the lack of standardized content determination methods.In the future,the development of URCR quality standards will focus on controlling its quality consistency and safety,with emphasis on precise identification of origins,validation of clinical effica-cy across different multi-source medicinal materials,development of multi-component quantitative analysis methods,and improvement of safety indicators.关键词
钩藤/多基原药材/质量标准/质量控制技术Key words
Uncariae Ramulus Cum Uncis/multi-source traditional Chinese medicine/quality standards/quality control technology分类
医药卫生引用本文复制引用
冀晓雯,付金娥,韦树根,万凌云,翟勇进,栗平,钟晟哲,李玉琼,梁文静,杨翠红,覃雅,张占江..钩藤质量标准历史沿革与质控技术研究进展[J].生物资源,2025,47(3):222-233,12.基金项目
国家自然科学基金项目(82360753) （82360753）
广西科技重大专项项目(桂科AA22096021) （桂科AA22096021）
广西自然科学基金项目(2019GXNSF-BA185026) （2019GXNSF-BA185026）
广西特色药材关键技术研究推广项目(GZKJ2314) （GZKJ2314）
广西中医药管理局项目(GXZYA20230009),2023年广西中医药多学科交叉创新团队(GZKJ2305)和广西岐黄学者培养项目(GXQH202402) （GXZYA20230009）
