川北医学院学报2025，Vol.40Issue(6)：799-802,4.DOI:10.3969/j.issn.1005-3697.2025.06.026
显微镜夹闭术与血管内介入栓塞术治疗颅内动脉瘤的比较研究
A comparative study of microscopic clipping and endovascular interven-tional embolization in the treatment of cerebral aneurysms
吴小聪 1彭宗军 1游潮 2陈辉1
作者信息
- 1. 四川友谊医院神经外科,四川 成都 610000
- 2. 四川大学华西医院神经外科,四川 成都 610041
- 折叠
摘要
Abstract
Objective:To explore the clinical value of microscopic clipping and endovascular interventional embolization in the treatment of cerebral aneurysms.Methods:A retrospective analysis was conducted on the clinical data of 90 patients with cerebral aneu-rysms.The patients were divided into clipping group and intervention group according to different surgical techniques,with 45 cases in each group.The perioperative indexes,vascular endothelial function and inflammatory factors before surgery and at 1 week after surgery,nerve function[National Institutes of Health Stroke Scale(NIHSS),Glasgow Outcome Scale(GOS)]at 6 months after surgery in the two groups were compared.Results:The perioperative indexes in intervention group were lower than those in clipping group(P＜0.05).At 1 week after surgery,levels of VEGF and ET-1 in intervention group were lower than those in clipping group(P＜0.05),while CGRP was higher than that in clipping group(P＜0.05).At 1 week after surgery,levels of MMP-9,TNF-α and HIF-1α in inter-vention group were lower than those in clipping group(P＜0.05).At6 months after surgery,NIHSS score in intervention group was lower than that in clipping group,while GOS score was higher than that in clipping group(P＜0.05).Conclusion:Endovascular inter-ventional embolization has advantages such as simple operation and fast postoperative recovery,which can effectively repair vascular and cerebral nerve injury,and reduce inflammatory response in patients with cerebral aneurysms.关键词
颅内动脉瘤/显微镜夹闭术/血管内介入栓塞术/神经功能/倾向性匹配评分Key words
Cerebral aneurysm/Microscopic clipping/Endovascular interventional embolization/Nerve function/Propensity matching score分类
医药卫生引用本文复制引用
吴小聪,彭宗军,游潮,陈辉..显微镜夹闭术与血管内介入栓塞术治疗颅内动脉瘤的比较研究[J].川北医学院学报,2025,40(6):799-802,4.
