磁共振成像2025，Vol.16Issue(5)：229-234,6.DOI:10.12015/issn.1674-8034.2025.05.035
磁共振波谱在血液系统疾病中的研究及应用进展
Research progress on the application of magnetic resonance spectroscopy in hematological diseases
摘要
Abstract
Hematological diseases are a kind of diseases with abnormal hematopoietic system accompanied by abnormal changes in blood,and most of these diseases have the characteristics of high mortality,and in recent years,their mortality rates have continued to rise.In terms of diagnosis,there is a lack of specific indicators for some hematologic diseases,and the current diagnosis mainly relies on bone marrow biopsy,but this examination is somewhat invasive and has low patient acceptance.And due to the uneven distribution of hematopoietic tissue,the examination results of different puncture sites were quite different.In addition,there is a significant time lag between bone marrow status and peripheral blood manifestations,and many of the above factors have led to great difficulties in diagnosis and many limitations in the process of clinical application.Magnetic resonance spectroscopy(MRS)is a non-invasive detection method that uses magnetic resonance phenomena and chemical shifts,and has significant advantages without damage.Based on the position,intensity,and fine structure of the formants in MRS,the structure and composition of compounds can be qualitatively and quantitatively studied.Due to technical limitations,MRS has not been widely used in clinical practice,and it is expected to become a routine clinical tool in the future with the deepening of research.This article will review the literature to review the research and application progress of MRS in hematological diseases such as leukemia,aplastic anemia(AA),myelodysplastic syndrome(MDS),etc.,in order to provide a basis and reference for the diagnosis and treatment of hematologic diseases.关键词
血液系统疾病/白血病/再生障碍性贫血/骨髓增生异常综合征/磁共振波谱/磁共振成像/诊断/监测Key words
hematological system diseases/leukemia/aplastic anemia/myelodysplastic syndrome/magnetic resonance spectroscopy/magnetic resonance imaging/diagnosis/monitor分类
医药卫生引用本文复制引用
闫红敏,高明洁,陈涛,付卿桦,张牛霖,岳辛如,任小云,刘旭,王金环..磁共振波谱在血液系统疾病中的研究及应用进展[J].磁共振成像,2025,16(5):229-234,6.基金项目
National Natural Science Foundation of China(No.82474490) （No.82474490）
Heilongjiang Province Traditional Chinese Medicine Research Project(No.ZHY2024-274). 国家自然科学基金项目(编号:82474490) （No.ZHY2024-274）
黑龙江省中医药科研课题项目(编号:ZHY2024-274) （编号:ZHY2024-274）
