南方医科大学学报2025，Vol.45Issue(6)：1113-1121,9.DOI:10.12122/j.issn.1673-4254.2025.06.01
高度近视合并散光治疗中Toric-ICL比FS-LASIK具有更好的可预测性和近视治疗效果
Toric-ICL shows better predictability and efficacy than FS-LASIK for myopia correction in patients with moderate to high myopia and astigmatism
摘要
Abstract
Objective To compare the efficacy of toric implantable collamer lens(Toric-ICL)and femtosecond laser-assisted in situ keratomileusis(FS-LASIK)for myopia correction in patients with moderate to high myopia complicated with astigmatism.Methods We retrospectively collected data from 64 patients(aged 18-42 years)with moderate to high myopia complicated with astigmatism(128 eyes)undergoing either Toric-ICL(28 patients/56 eyes)or FS-LASIK(36 patients/72 eyes)at our department between January,2019 and December,2020.The changes of uncorrected distance visual acuity(UCVA),spherical equivalent(SE),mean astigmatism correction index(CI),corneal endothelial cell density(ECD)and intraocular pressure(IOP)following the procedures were compared between the two groups.Results In FS-LASIK group,all the eyes(72/72)achieved an UCVA≥1.0,similar to the rate in Toric-ICL group(55/56 eyes;P=0.2374).The postoperative SE was also comparable between FS-LASIK and Toric-ICL groups[0.43±0.06 D(range:-1.0 to 1.50 D)vs 0.38±0.05 D(range:-0.75 to 1.00 D);P=0.56].The mean astigmatism CI was significantly higher in FS-LASIK group than in Toric-ICL group(0.8561 vs 0.7176;P<0.0001),and 88.89%of the eyes in FS-LASIK group and 69.64%in Toric-ICL group had postoperative astigmatism≤0.50 D.No significant changes were observed in postoperative corneal ECD in FS-LASIK group,whereas ECD decreased significantly after the procedure in Toric-ICL group(P=0.0057).The patients undergoing Toric-ICL exhibited no significant changes of postoperative IOP,but the patients receiving FS-LASIK had significantly reduced IOP after the procedure(P<0.001).Conclusion Although the patients included in Toric-ICL group had higher myopia and astigmatism,Toric-ICL still showed better predictability and efficacy for astigmatic correction in Toric-ICL group.Toric-ICL is an effective and safe equivalent of FS-LASIK for correcting moderate myopia but can be more advantageous for correcting high myopia with astigmatism.关键词
散光型有晶体眼人工晶状体/飞秒激光辅助准分子激光原位角膜磨镶术/近视/散光/治疗效果Key words
toric implantable collamer lens/femtosecond laser-assisted in situ keratomileusis/myopia/astigmatism/treatment effect引用本文复制引用
李红阳,陈美兰,廖文雄,雷鹏,杨春园,黎燕英,薛丽萍,谭朵,刘思静,吴艺..高度近视合并散光治疗中Toric-ICL比FS-LASIK具有更好的可预测性和近视治疗效果[J].南方医科大学学报,2025,45(6):1113-1121,9.基金项目
Supported by Guangdong Provincial Medical Research Foundation(B2023041) （B2023041）
Special Project for the Construction and Enhancement of Double First-Class Disciplines(2023B10564003) （2023B10564003）
Joint Fund of Basic and Applied Basic Research Fund of Guangdong Province(2024A03J0992) （2024A03J0992）
Guangdong Provincial Natural Science Foundation for Basic and Applied Basic Research Project(2024A1515012868). 广东省医学科学技术研究基金(B2023041) （2024A1515012868）
双一流学科建设和提升专项(2023B10564003) （2023B10564003）
广州市科技计划项目(2024A03J0992) （2024A03J0992）
广东省基础与应用基础研究自然科学基金(2024A1515012868) （2024A1515012868）
