康复学报2025，Vol.35Issue(3)：284-290,7.DOI:10.3724/SP.J.1329.2025.03008
社区老年人群呼吸功能和可能肌少症的相关性研究
Association between Respiratory Function and Possible Sarcopenia in Community-Dwelling Elderly Population
摘要
Abstract
Objective To investigate the characteristics of respiratory function changes and their association with possible sar-copenia in community-dwelling elderly population.Methods A total of 3,538 elderly individuals with possible sarcopenia,who visited Qiaobei Community Hospital(Nanjing Jiangbei New District),Huayang Community Hospital(Jurong City),and the Second People's Hospital of Sheyang County(Yancheng)from May 2021 to September 2023,were enrolled.According to the 2019 Asian Working Group for Sarcopenia diagnostic criteria for possible sarcopenia,the participants were divided into two groups:the possible sarcopenia group(1,355 cases)and the non-sarcopenia group(2,183 cases).A structured questionnaire was utilized to collect demo-graphic data,behavioral characteristics,dietary habits,and nutritional status.Respiratory muscle strength was evaluated using a re-spiratory muscle strength tester to measure maximal inspiratory pressure(MIP)and maximal expiratory pressure(MEP).A portable spirometer was employed to assess forced vital capacity(FVC),forced expiratory volume in the first second(FEV1),and FEV1/FVC ratio.Grip strength was determined using an electronic dynamometer.Body composition parameters,including skeletal muscle mass percentage(SM%)and percent body fat(PBF%),were measured via bioelectrical impedance analysis.Functional mobility was as-sessed using a waist-worn wearable device to record the time required for five times sit-to-stand test and gait speed.The associations between respiratory function changes and sarcopenia-related parameters were analyzed.Results The prevalence of possible sarco-penia in the elderly cohort was 38.30%,with rates of 39.31%in males and 37.13%in females.Compared to the non-sarcopenia group,the males with possible sarcopenia exhibited a significantly lower participation in regular physical activity(P<0.05),higher malnutrition risk(P<0.05),lower BMI and grip strength(P<0.05),and impaired respiratory function(lower MIP,MEP,and FEV1;P<0.05).In females with possible sarcopenia,physical activity participation,calf circumference,and SM%were significantly lower than those in the non-sarcopenia group(P<0.05),while malnutrition risk was higher(P<0.05).Respiratory function parameters,in-cluding MIP,MEP,FVC,and FEV1/FVC,were also significantly lower in this group(P<0.05).In males,MIP,MEP,and FEV1/FVC showed positive correlations with calf circumference(P<0.05).Age was positively correlated with PBF%(P<0.05),whereas MIP,FVC,and FEV1/FVC were inversely correlated with PBF%(P<0.05).MIP,MEP,FVC,and FEV1/FVC were positively correlated with SM%and gait speed(P<0.05).In females,MIP,MEP,and FEV1/FVC were positively correlated with calf circumference(P<0.05).Age was positively associated with PBF%while MIP,FVC,and FEV1/FVC were negatively correlated with PBF%(P<0.05).Age was negatively correlated with SM%(P<0.05),while MIP and FEV1/FVC demonstrated positive correlations with SM%(P<0.05).MIP,MEP,and FVC were positively correlated with gait speed(P<0.05).Logistic regression analysis identified age,alcohol consumption history,BMI,MIP,FEV1 and FEV1/FVC as independent risk factors for possible sarcopenia(P<0.05).Conclusion El-derly individuals with possible sarcopenia exhibit significant declines in respiratory function.Respiratory parameters,including MIP,MEP,FVC,FEV1 and FEV1/FVC,are correlated with possible sarcopenia assessment indicators.Aging,alcohol consumption,lower BMI and impaired respiratory function are critical risk factors for possible sarcopenia.关键词
可能肌少症/呼吸功能/呼吸肌肌力/老年人群/相关性分析Key words
possible sarcopenia/respiratory function/respiratory muscle strength/elderly population/correlation analysis引用本文复制引用
孙梓涵,方蕾雯,周停,罗升,杨晓玲,刘娟,王红星,姚捷..社区老年人群呼吸功能和可能肌少症的相关性研究[J].康复学报,2025,35(3):284-290,7.基金项目
国家重点研发计划基金项目(2022YFC2009700) （2022YFC2009700）
江苏省重点研发计划社会发展项目(BE2020718) （BE2020718）
江苏省卫生健康发展研究中心项目(JSHDRC2021030) （JSHDRC2021030）
江苏省教育厅哲学社会科学重点研究基地基金(2020B02) （2020B02）
