广西医科大学学报2025，Vol.42Issue(3)：475-482,8.DOI:10.16190/j.cnki.45-1211/r.2025.03.021
2023-2024年我国真菌病临床实践指南与共识质量评价:基于AGREEⅡ工具的研究
Quality assessment of clinical practice guidelines and consensuses for fungal diseases in China from 2023 to 2024:a study based on the AGREEⅡ
王孝盼 1廖万清 1尚梦雅 1方文捷 1杜明威 1朱信霖 1殷奇 1刘晓刚 1潘炜华 1刘伊诺1
作者信息
- 1. 海军军医大学第二附属医院皮肤科 上海市医学真菌分子生物学重点实验室,上海 200003
- 折叠
摘要
Abstract
Objective:To systematically assess the methodological quality of clinical practice guidelines for fun-gal diseases to provide a reference for the formulation of guidelines/consensuses in the field of fungal diseases in the future.Methods:Guidelines and expert consensuses on fungal diseases were searched from relevant data-bases and related websites such as Medline(via PubMed),Embase,China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform,Chinese Biomedical Literature Database,China Clinical Guidelines Library Network,and China Medical Knowledge Base Guidelines Library from January 2023 to De-cember 2024.After two researchers completed the consistency evaluation,the included guidelines and consen-suses were evaluated for methodological quality and the results were analyzed using the Appraisal of Guidelines for Research&Evaluation(AGREE)instrumentⅡ,also known as AGREEⅡ.Results:Twenty-two guidelines or consensuses were finally included,of which 8 were rated as grade A(recommended for adoption)and 14 were rated as grade B(recommendable after modification).The scoring rates of the six domains evaluated by AGREEⅡ were 8.21%±1.52%for Scope and Purpose,65.53%±0.79%for Stakeholder Involvement,68.94%±0.23%for Rigour of Development,80.81%±0.45%for Clarity of Presentation,6.35%±0.52%for Applicability,and 67.99%±4.09%for Independence.Failure to document and disclose conflicts of interest among guideline development group members in terms of independence was a significant factor for score deduction.The guidelines/consensuses in 2024 were superior to those in 2023 in terms of rigour(P＜0.05).Conclusion:The methodological quality of fungal disease guidelines and expert consensuses regarding participants,rigour,applicability,and independence needs to be further improved,and the guideline development needs to be in strict accordance with AGREEⅡ re-quirements to clarify conflicts of interest.关键词
真菌病/临床实践指南/专家共识/指南研究与评价系统Ⅱ/方法学质量评价Key words
fungal diseases/clinical practice guidelines/expert consensuses/the Appraisal of Guidelines for Re-search&Evaluation instrumentⅡ/methodological quality assessment分类
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王孝盼,廖万清,尚梦雅,方文捷,杜明威,朱信霖,殷奇,刘晓刚,潘炜华,刘伊诺..2023-2024年我国真菌病临床实践指南与共识质量评价:基于AGREEⅡ工具的研究[J].广西医科大学学报,2025,42(3):475-482,8.
