江汉大学学报（自然科学版）2025，Vol.53Issue(3)：48-55,8.DOI:10.16389/j.cnki.cn42-1737/n.2025.03.006
线粒体调控免疫细胞的分子机理研究进展
Advances in Molecular Mechanisms of Mitochondrial Regulation of Immune Cells
摘要
Abstract
As an important organelle,mitochondria,the site of cellular metabolic substance synthesis and energy production,are involved in many important biological processes,such as cell proliferation,differentiation,and apoptosis.Immune cells are the main components of the immune system and have an important impact on maintaining the immune homeostasis of the body.In recent years,more studies have revealed the importance of mitochondrial metabolism in immune cells,e.g.,mitochondria can release signals such as mitochondrial DNA and mitochondrial reactive oxygen species to regulate immune cell activation,differentiation,and function.Changes in mitochondrial metabolism may be the underlying cause of immunocytopenia or immune cell damage.Here,we reviewed the role of mitochondrial metabolism in immune cells and provided an overview of current research progress on the effects of mitochondrial metabolism on immune cells.关键词
线粒体代谢/免疫细胞/氧化磷酸化/脂肪酸氧化/氨基酸代谢Key words
mitochondrial metabolism/immune cells/oxidative phosphorylation/fatty acid oxidation/amino acid metabolism分类
医药卫生引用本文复制引用
夏雯雯,郑诗琼,欧阳礼辰,龚业莉..线粒体调控免疫细胞的分子机理研究进展[J].江汉大学学报（自然科学版）,2025,53(3):48-55,8.基金项目
国家级大学生创新训练项目(202211072019) （202211072019）
江汉大学校级自然科学基金项目(2021yb135) （2021yb135）
