机器人外科学杂志（中英文）2025，Vol.6Issue(6)：999-1007,9.DOI:10.12180/j.issn.2096-7721.2025.06.023
新辅助免疫治疗联合化学治疗后食管癌微创术式选择
Minimally invasive surgery options for esophageal cancer following neoadjuvant immunotherapy combined with chemotherapy
摘要
Abstract
Objective:To compare the therapeutic efficacy of robot-assisted minimally invasive esophagectomy(RAMIE)versus video-assisted minimally invasive esophagectomy(VAMIE)in esophageal cancer patients who underwent neoadjuvant immunotherapy combined with chemotherapy.Methods:Clinical data from esophageal cancer patients who underwent RAMIE or VAMIE following neoadjuvant therapy combined with chemotherapy were retrospectively analyzed.Operative time,postoperative complication rates(particularly pulmonary inflammation),and overall prognosis were evaluated.Results:The RAMIE group showed a longer operative time than the VAMIE group,though the difference was not statistically significant.The overall postoperative complication rate was lower in the RAMIE group than that in the VAMIE group,with a significantly reduced incidence of pulmonary inflammation(P=0.020).No significant difference was observed in survival outcomes between the two groups.Conclusion:For esophageal cancer patients received neoadjuvant immunotherapy combining with chemotherapy,RAMIE is a safe and feasible minimally invasive approach,which has a lower postoperative complication rate but comparable survival benefits compared to VAMIE,particularly in pulmonary inflammation.关键词
食管癌/新辅助治疗/手术方式/机器人辅助手术/腔镜手术Key words
Esophageal Cancer/Neoadjuvant Therapy/Surgical Method/Robot-assisted Surgery/Endoscopic Surgery分类
临床医学引用本文复制引用
唐慕虎,许正超,汪路明,朱林海,林旭,王一青,吕望,叶芃,胡坚..新辅助免疫治疗联合化学治疗后食管癌微创术式选择[J].机器人外科学杂志（中英文）,2025,6(6):999-1007,9.基金项目
国家重点研发计划(2022YFC2407303) （2022YFC2407303）
浙江省重点研发计划(2022C04030) （2022C04030）
中国博士后科学基金第17批特别资助(2024T170809)National Key Research and Development Program of China(2022YFC2407303) （2024T170809）
Zhejiang Provincial Key Research and Development Program(2022C04030) （2022C04030）
Special Funding of the 17th Batch of China Postdoctoral Science Foundation(2024T170809) （2024T170809）
