全科护理2025，Vol.23Issue(12)：2194-2200,7.DOI:10.12104/j.issn.1674-4748.2025.12.004
家庭护士食疗模式在超重/肥胖代谢相关脂肪性肝病病人中的应用
Study on the application of family nurse diet therapy mode in overweight/obese patients with metabolic dysfunction-associated fatty liver disease
摘要
Abstract
Objective:To verify the effectiveness of the family nurse diet therapy mode guided by the family nurse diet therapy theory in overweight/obese patients with metabolic dysfunction-associated fatty liver disease.Methods:From August to November 2024,a total of 106 overweight/obese patients with metabolic dysfunction-associated fatty liver disease were recruited from the community.A personalized dietary intervention was implemented based on the dietary prescription and family nurse dietary therapy products derived from the family nurse diet therapy theory.The changes in various clinical indicators of the subjects were observed after 6 weeks of intervention.Results:After 6 weeks of intervention,all indicators of body composition in the subjects were significantly improved(P<0.05).Compared to baseline,the values of liver steatosis analysis(LiSA),liver elasticity measurement(E),fasting plasma glucose(FPG),fasting serum insulin(FINS),homeostatic model assessment of insulin resistance(HOMA-IR),total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),high sensitivity C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),malondialdehyde(MDA),alanine aminotransferase(ALT),aspartate aminotransferase(AST),and uric acid(UA)all decreased(P<0.05).Meanwhile,the levels of superoxide dismutase(SOD)increased compared to baseline(P<0.05).Blood urea nitrogen(BUN),serum creatinine(SCr)and high-density lipoprotein cholesterol(HDL-C)showed no significant difference before and after intervention(P>0.05).The self-management score for fatty liver improved(P<0.05).Conclusions:This dietary therapy mode can significantly improve patients'body composition,reduce fatty liver,regulate glucose and lipid metabolism,control inflammation and oxidative stress,protect liver and kidney function,enhance patients'self-management ability for fatty liver,and help develop good dietary habits.It offers new insights and effective methods for dietary therapy in overweight/obese patients with metabolic dysfunction-associated fatty liver disease.关键词
超重/肥胖/代谢相关脂肪性肝病/家庭护士食疗理论/饮食模式/护理Key words
overweight/obesity/metabolic associated fatty liver disease/family nurse diet therapy theory/dietary pattern/nursing分类
医药卫生引用本文复制引用
宋杰,韩世范,赵瑜,潘梦怡,董妞妞,赵奕雯,程俊香,张欢,朱瑞芳..家庭护士食疗模式在超重/肥胖代谢相关脂肪性肝病病人中的应用[J].全科护理,2025,23(12):2194-2200,7.基金项目
山西省食疗和农产品处方产业技术创新战略联盟项目. （）
