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骨骼干细胞的研究进展

陈晓帆 王佐林

口腔颌面外科杂志2025,Vol.35Issue(3):219-222,4.
口腔颌面外科杂志2025,Vol.35Issue(3):219-222,4.DOI:10.12439/kqhm.1005-4979.2025.03.008

骨骼干细胞的研究进展

Research advances in skeletal stem cells

陈晓帆 1王佐林1

作者信息

  • 1. 上海市同济口腔医院口腔种植科,同济大学口腔医学院,上海牙组织修复与再生工程技术研究中心,同济大学口腔医学研究所,上海 200072
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摘要

Abstract

The development,homeostasis maintenance,and damage repair of the skeletal system require continuous proliferation and differentiation of stem and progenitor cells.Although studies on bone marrow mesenchymal stem cells(BMSCs)have accumulated substantial evidence over the past decades,the definition and markers of skeletal stem cells(SSCs)remain controversial.Recent advances in lineage tracing and bioinformatics technologies have facilitated the purification and functional investigation of SSCs.This review systematically summarizes different SSC populations based on their origins and markers,as well as their functions in skeletal development and repair.

关键词

骨骼干细胞/骨髓间充质干细胞/骨修复/骨发育

Key words

skeletal stem cells/bone marrow mesenchymal stem cells/bone repair/bone development

分类

口腔医学

引用本文复制引用

陈晓帆,王佐林..骨骼干细胞的研究进展[J].口腔颌面外科杂志,2025,35(3):219-222,4.

基金项目

国家重点研发计划(2018YFE0202200) (2018YFE0202200)

口腔颌面外科杂志

1005-4979

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