华西口腔医学杂志2025，Vol.43Issue(3)：383-394,12.DOI:10.7518/hxkq.2025.2024418
封闭剂与氟保护漆预防儿童第一恒磨牙咬合面龋的Meta分析
Meta-analysis of sealants versus fluoride varnishes for the prevention of occlusal surface caries in children's first permanent molars
韩静雅 1张雅钧 1冀梦真 1孙景飞 1贾书涵 2王志峰1
作者信息
- 1. 山东大学齐鲁医学院口腔医学院·口腔医院儿童口腔科 山东省口腔组织再生重点实验室 口腔生物材料与组织再生山东省工程研究中心 山东省口腔疾病临床医学研究中心,济南 250012
- 2. 盐城市第一人民医院口腔科,盐城 224000
- 折叠
摘要
Abstract
Objective To assess the effectiveness of the comparison between pit and fissure sealants and fluoride var-nishes,as well as various types of sealants,in preventing caries on the occlusal surface of children's first permanent mo-lars(FPM).Methods Conduct a comprehensive search of literature published between January 1,1988,and May 30,2024,in the following databases:China National Knowledge Infrastructure,Web of Science,Cochrane Library,Embase,PubMed,China Science Periodical Database and China Biology Medicine database.Meta-analysis and subgroup analy-ses were performed on the literature that met the inclusion criteria.Results A total of 5 618 pieces of literature were re-trieved,resulting in the inclusion of 14 in the study.Meta-analysis showed that there was no statistically significant dif-ference in the efficacy between varies pit and fissure sealants compared to fluoride varnishes,and between varies types of sealants in preventing caries on the occlusal surface of children's first permanent molars within 24 months post-surgery(P＞0.05).Conclusion Within 24 months,there was no significant difference in the effectiveness of using resin-based or glass iomomer pit and fissure sealants compared with fluoride varnishes in preventing occlusal caries in FPM in children;within 24 months,there was no significant difference in the effectiveness of using resin-based sealants compared with ART sealants in preventing occlusal caries in FPM in children.ART sealants are recommended over resin-based sealers for children who have no conditions for chair-side manipulation or who are poorly co-operative.关键词
窝沟封闭剂/氟保护漆/第一恒磨牙/龋病预防/Meta分析Key words
pit and fissure sealant/fluoride varnish/first permanent molar/caries prevention/Meta-analysis分类
医药卫生引用本文复制引用
韩静雅,张雅钧,冀梦真,孙景飞,贾书涵,王志峰..封闭剂与氟保护漆预防儿童第一恒磨牙咬合面龋的Meta分析[J].华西口腔医学杂志,2025,43(3):383-394,12.
