临床口腔医学杂志2025，Vol.41Issue(6)：328-333,6.DOI:10.3969/j.issn.1003-1634.2025.06.003
纳米银联合EDTA对根管内牙本质微观结构及力学性能的影响研究
Effects of silver nanoparticles combined with EDTA on the microstructure and mechanical properties of root canal dentin
摘要
Abstract
Objective:To evaluate the effects of 0.1％ silver nanoparticles(AgNPs)combined with EDTA on the mi-crostructure and mechanical properties of intraradicular dentin.Methods:Totally 110 single-rooted human premolars were mechanically prepared and randomly divided into five experimental groups(n=20)and one control group(n=10).Experi-mental groups:Group A(0.1％ AgNPs),Group B(3％ NaClO),Group C(0.1％AgNPs+17％EDTA),Group D(3％ NaClO+17％EDTA),Group E(0.9％saline).Ten teeth from each experimental group were longitudinally split for smear layer remov-al assessment via scanning electron microscopy(SEM)and microhardness testing.Dentin powder from root canal walls of all groups(including control)was analyzed by Fourier transform infrared spectroscopy(FTIR).Results:At coronal and middle thirds,Groups C and D showed significantly better smear layer removal than Groups A,B,and E(P＜0.05),with no signifi-cant difference between Groups C and D(P＞0.05).At the coronal third,Groups A and C exhibited higher microhardness than Groups B and D(P＜0.05),at the middle third,Group A demonstrated greater hardness than Groups B,C,and D(P＜0.05).FTIR analysis revealed:carbonate/mineral ratio was higher in Group D than Group C(P＜0.05),amide I/mineral ra-tio in Group B was lower than the control group(P＜0.05),while Group D surpassed Group C(P＜0.05).Conclusion:AgNPs combined with EDTA effectively removed the smear layer,exhibited weaker collagen-deproteinizing effects,and caused minimal impact on dentin microhardness.关键词
根管冲洗/纳米银/玷污层/力学性能Key words
Root canal irrigation/Silver nanoparticles/Smear layer/Mechanical properties分类
口腔医学引用本文复制引用
李美云,张昊,周永庆..纳米银联合EDTA对根管内牙本质微观结构及力学性能的影响研究[J].临床口腔医学杂志,2025,41(6):328-333,6.基金项目
湖北省教育厅科学技术研究项目(编号:B2022133) （编号:B2022133）
