农业生物技术学报2025，Vol.33Issue(7)：1626-1635,10.DOI:10.3969/j.issn.1674-7968.2025.07.018
组蛋白乳酸化在动物生殖发育中的研究进展
Research Progress on Histone Lactylation in Animal Reproductive Development
摘要
Abstract
Epigenetic modification plays an important role in a series of reproductive developments such as spermatogenesis,oogenesis,early embryonic development,embryo implantation,and stem cells.Histone lactylation,as a newly discovered epigenetic modification that links cellular metabolism with epigenetic regulation,is gradually deepening the study of its mechanism of action in animal reproductive development.In this paper,the latest research progress on histone lactylation were summarized,focusing on the close relationship between histone lactylation and other apparent modifications,the writer,reader and eraser of histone lactylation modifications,and the role of histone lactylation in animal reproductive development.This paper systematically reviewed the research progress of histone lactylation modification in animal repro-ductive development,provides a theoretical basis for a deeper understanding of the molecular regulatory mechanisms of reproductive development.关键词
组蛋白乳酸化/生殖发育/表观遗传Key words
Histone lactylation/Reproductive development/Epigenetic分类
畜牧业引用本文复制引用
夏翌,王智超,史振虎,汪薪,张运海,曹祖兵..组蛋白乳酸化在动物生殖发育中的研究进展[J].农业生物技术学报,2025,33(7):1626-1635,10.基金项目
国家重点研发计划(2023YFD1300502-1) （2023YFD1300502-1）
安徽省自然科学基金面上项目(2308085NC98) （2308085NC98）
胚胎发育与生殖调节安徽省重点实验室开放课题(FSKFKT004) （FSKFKT004）
