山东农业大学学报（自然科学版）2025，Vol.56Issue(3)：444-451,8.DOI:10.3969/j.issn.1000-2324.2025.03.008
Zn,Al-CDs对四环素类抗生素的超灵敏荧光检测
Ultrasensitive Fluorescence Detection of Tetracycline Antibiotics by Zn,Al-CDs
摘要
Abstract
Tetracycline antibiotics(TCs)are widely used in medicine and aquaculture.Their residues pose a threat to food safety and the ecological environment.Therefore,it is crucial to develop efficient and sensitive detection methods for TCs.This study utilizes sodium citrate as the carbon source,incorporates Zn and Al doping,and synthesizes carbon dots(Zn,Al-CDs)through a hydrothermal method.By employing these carbon dots as fluorescent probes,ultrasensitive fluorescence detection of TC is achieved.With the increase of TCs concentration,the detection system exhibits green fluorescence,and a good linear connection is observed between fluorescence intensity and TCs concentration.The detection system has linear ranges of 0.01～7 μM,0.01～7 μM,0.01～5 μM,and 0.01～7 μM for tetracycline hydrochloride(TCH),chlortetracycline hydrochloride(CTC),oxytetracycline hydrochloride(OTC),and doxycycline hydrochloride(DOC),respectively,with detection limits of 5.6 nM,7.41 nM,4.28 nM,and 13.5 nM,respectively.Different types of tetracyclines are distinguished by the emission wavelength of the systemic fluorescence.In addition,the Zn,Al-CDs material is successfully applied to detect TCH in tap water,river water and milk,and the paper-based sensor prepared with Zn,Al-CDs can achieve semi-quantitative visual detection of TCs,indicating the material's potential as a qualitative and quantitative detection sensor for tetracycline antibiotics.关键词
四环素/碳点/检测/荧光Key words
Tetracyclines/carbon dots/detection/fluorescence分类
化学引用本文复制引用
郭风静,王捷,段志雨,付全彬,张元红,侯芹,李怡靖..Zn,Al-CDs对四环素类抗生素的超灵敏荧光检测[J].山东农业大学学报（自然科学版）,2025,56(3):444-451,8.基金项目
四川省高盐废水处置及资源化工程技术研究中心(四川轻化工大学)开放基金资助课题(SCGCY2302) （四川轻化工大学）
