摘要
Abstract
Objective:To discuss the relationship between the incidence rate of coronary atherosclerotic heart disease and inflammatory factors in patients with type 2 diabetes.Methods:203 patients with type 2 diabetes admitted to Jiuquan Hospital(Jiuquan People's Hospital)of Shanghai First People's Hospital from January 2022 to August 2024 were followed up.Among them,80 patients who were admitted to the cardiovascular department due to chest pain and chest distress were taken as the study subjects,and coronary angiography was performed.According to the re-sults,they were divided into coronary heart disease group(n=38)and non coronary heart disease group(n=42);Select healthy individuals who came to the hospital for physical examinations during the same period as the refer-ence group(n=40).All three groups of research subjects underwent inflammation factor index testing,and the levels of inflammatory factors such as high-sensitivity C-reactive protein,tumor necrosis factor-a,and interleu-kin-6 were compared among the three groups.Logistic regression analysis was used to identify independent risk factors.Results:The levels of high-sensitivity C-reactive protein,tumor necrosis factor-α,and interleukin-6 in both coronary heart disease and non coronary heart disease groups were higher than those in the control group.At the same time,the levels of these three inflammatory factors were higher in the coronary heart disease group than in the non coronary heart disease group,P<0.05.The age of the coronary heart disease group is higher than that of the non coronary heart disease group,and the levels of triglycerides and total cholesterol are higher than those of the non coronary heart disease group,P<0.05.Logistic regression analysis showed that triglycerides,to-tal cholesterol,and three inflammatory factors were independent risk factors for coronary heart disease(P<0.05).Conclusion:Type 2 diabetes is associated with coronary heart disease.Inflammatory factors are involved in the oc-currence of coronary heart disease in patients with type 2 diabetes.关键词
2型糖尿病/冠状动脉粥样硬化性心脏病/危险因素Key words
Type 2 diabetes/Coronary atherosclerotic heart disease/Risk factors分类
医药卫生
