饲料研究2025，Vol.48Issue(9)：155-159,5.DOI:10.13557/j.cnki.issn1002-2813.2025.09.027
基于斑马鱼模型探讨中草药提取物的抗炎抗氧化作用
Exploring anti-inflammatory and antioxidant effects of Chinese herbal extracts based on zebrafish modeling
摘要
Abstract
Inflammation and oxidative stress are the pathological basis of various diseases,making the study of their prevention and treatment strategies highly significant.Zebrafish,due to its unique biological characteristics,has become an ideal model for evaluating the anti-inflammatory and antioxidant effects of drugs.Active components of Chinese herbal extracts,such as baicalin,ShenFuHuang formula extract,and quercetin,have demonstrated significant anti-inflammatory and antioxidant effects in zebrafish models.These effects are achieved through mechanisms including the modulation of inflammation-related signaling pathways,inhibition of inflammatory mediator release,and scavenging of free radicals.Compared to synthetic drugs,herbal extracts offer advantages such as multi-component,multi-target effects,low toxicity,and high bioavailability,offering a new avenue for the development of anti-inflammatory and antioxidant drugs.This paper reviews the research progress of Chinese herbal extracts for anti-inflammatory and antioxidant purposes using zebrafish models,explores their mechanisms of action,and provides reference for the application of Chinese herbal extracts in animal production.关键词
斑马鱼/模式动物/中草药提取物/抗炎/抗氧化Key words
zebrafish/model animal/Chinese herbal extract/anti-inflammatory/antioxidation分类
畜牧业引用本文复制引用
周蔓,安晓萍,王园,刘娜,王文文,郑越,齐景伟..基于斑马鱼模型探讨中草药提取物的抗炎抗氧化作用[J].饲料研究,2025,48(9):155-159,5.基金项目
内蒙古自治区"英才兴蒙"工程团队项目(项目编号:2025TYL10),内蒙古自治区教育厅一流学科科研专项项目(项目编号:YLXKZX-NND-007) （项目编号:2025TYL10）
