四川环境2025，Vol.44Issue(3)：87-95,9.DOI:10.14034/j.cnki.schj.2025.03.012
小体积液液萃取-高效液相色谱串联质谱法测定水中烷基酚和双酚A
Determination of Alkylphenols and Bisphenol A in Water Using Small-Volume Liquid-Liquid Extraction Coupled with High-Performance Liquid Chromatography-Tandem Mass Spectrometry
摘要
Abstract
This study aims to establish a simple,rapid,efficient,and highly sensitive method for the simultaneous detection of eight alkylphenols(APs)and bisphenol A(BPA)in surface water using a small-volume liquid-liquid extraction coupled with high-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS).Surface water samples were extracted with acetonitrile,vortex-mixed and allowed to stand,then the upper clear liquid was filtered.The samples were separated by liquid chromatography and detected by mass spectrometry.Identification was based on retention time,MS fragment ions,and their abundances,with quantification using an internal standard method.Results showed that the calibration curves for the analytes were linear in the range of 0.2-5.0 μg/L,with correlation coefficients greater than 0.998;the detection limits ranged from 0.025 to 0.08 μg/L.The relative standard deviations(n=6)for target compounds at concentrations of 0.1,0.5,and 2.0μg/L ranged from 1.5％to 17％,and the recoveries of spiked samples were between 69.3％and 128％.Applying this method to detect surface water samples from Sichuan Province,bisphenol A,nonylphenol,and octylphenol were detected.The recoveries of APs and BPA in real samples ranged from 62.2％to 122％.The results demonstrate that this method is simple to operate,highly sensitive,and suitable for detecting trace levels of APs and BPA in surface water.关键词
烷基酚/双酚A/小体积液液萃取/高效液相色谱质谱联用/地表水Key words
Alkylphenol/bisphenol A/small volume liquid-liquid extraction/high-performance liquid chromatography-mass spectrometry(HPLC-MS/MS)/surface water分类
资源环境引用本文复制引用
程欢,史箴,余恒,王若男,唐小淋,罗碧容,熊杰..小体积液液萃取-高效液相色谱串联质谱法测定水中烷基酚和双酚A[J].四川环境,2025,44(3):87-95,9.基金项目
四川省生态环境保护科技项目(2023HB05). （2023HB05）
