日用化学工业（中英文）2025，Vol.55Issue(6)：715-722,8.DOI:10.3969/j.issn.2097-2806.2025.06.005
经表皮失水率测量影响因素剖析及标准化操作研究
Analysis of the influencing factors and study on the standardized operation of transepidermal water loss measurement
摘要
Abstract
The transepidermal water loss(TEWL)of human skin is affected by many factors.Different test schemes were designed to systematically compare the test results of the cheek and inner forearm and other areas of healthy subjects,and explore the influence of measurement methods,environmental conditions,test site,instruments and equipment on TEWL test results.The results show that different test methods(including different measurement modes,interval time between two measurement,subject waiting time and accumulated multiple measurements)affect the reproducibility of the test results,and TEWL test results are significantly different under different conditions of environment temperature and humidity that skin surface contact,facial test site and day and night time.There is a strong correlation between the test results of different types of TEWL instruments,but the test stability is significantly different.In this study,various factors affecting the measurement of transepidermal water loss are systematically analyzed,and a standardized operation method is established to provide reliable and scientific technical support for accurate evaluation of the efficacy of cosmetics.关键词
经表皮失水率/影响因素/功效评价/标准化Key words
transepidermal water loss/influencing factors/efficacy evaluation/standardization分类
化学化工引用本文复制引用
陈凤玲,王亚茹,叶蓉姿,梁嘉恩,谢嘉颖,谭建华..经表皮失水率测量影响因素剖析及标准化操作研究[J].日用化学工业（中英文）,2025,55(6):715-722,8.基金项目
广州市科技计划项目(2023B04J0407) （2023B04J0407）
广州市市场监督管理局科技项目(2022KJ03) （2022KJ03）
广州市市场监督管理局知识产权助力关键技术科研攻关项目 （）
