生物信息学2025，Vol.23Issue(2)：152-164,13.DOI:10.12113/202310014
线粒体核糖体蛋白基因中最末内含子与其他内含子间的相互作用
Interactions between the last introns and other introns in mitochondrial ribosomal protein genes
摘要
Abstract
Previous related researches have shown that the interaction relationship between the first intron and other introns may be closely related to the regulation of gene expression.In order to discovery if is there the same interaction between the final intron and other introns?In this work,the sequences of mitochondrial ribosomal protein genes were selected as the samples,the optimal matched segments between the last intron and the reverse complementary sequences of other introns of each gene were obtained,and the characteristics of the optimal matched segments were analyzed,and these characteristics with the characteristics of the optimal matched for interactions between the first introns and other introns were compared.It was found that the distributional characteristics of the length,GC content,and matching rate of the two kinds of optimal matched segments had the same trend with the five species,but the relative position frequencies of the optimal matched segments have very distinct different,it means the first intron and the last intron interacted with the other introns with some differences,implying that they were conserved in terms of the structure of the basic elements of the interactions,whereas they might be differentiated in terms of the roles of the regulation of gene expression.关键词
局域比对/最末内含子/最佳匹配片段/线粒体核糖体蛋白/相互作用Key words
Local matched alignment/Last intron/Optimal matched segments/Mitochondrial ribosomal protein genes/Interaction分类
生物学引用本文复制引用
高姗,宋鑫伟,彭诗雅,邓俊超,田旭,李瑞芳..线粒体核糖体蛋白基因中最末内含子与其他内含子间的相互作用[J].生物信息学,2025,23(2):152-164,13.基金项目
内蒙古自治区自然科学基金资助项目(No.2023MS03019). （No.2023MS03019）
