现代妇产科进展2025，Vol.34Issue(6)：425-428,436,5.DOI:10.13283/j.cnki.xdfckjz.2025.06.002
2014至2021年新疆地区妇女高危型HPV感染特点及趋势分析
Characteristics and trends of high-risk HPV infection in women in Xinjiang from 2014 to 2021
摘要
Abstract
Objective:To investigate the characteristics and trends in the positive rate of high-risk human papillomavirus(HR-HPV)infection among women in Xinjiang.Methods:A retrospective analysis was conducted on the infection status and characteristics of 135 466 women who underwent HR-HPV screening at the Gynecological Outpatient Clinic and Health Examination Center of the People's Hospital of Xinjiang Uygur Autonomous Region from Januar-y 2014 to December 2021.HPV DNA testing was performed using the QIAGEN Hybrid Capture 2(HC2)method,and HPV genotyping was conducted using the PCR-based flow-through hy-bridization method(Kai Pu).Results:From 2014 to 2021,the HR-HPV positive rate among women undergoing health examinations showed a yearly decline,decreasing by 37.3%over eight years,while no significant change was observed in the positive rate among opportunistic screening participants from the gynecological outpatient clinic.The highest HR-HPV positive rate was observed in the≥60 years age group,followed by the≤29 years group,with statisti-cally significant differences across age groups(P<0.001).The top eight prevalent HR-HPV subtypes in Xinjiang were,in order:types 16,52,58,39,53,51,31,and 66.Single HR-HPV in-fections predominated,and the distribution of multiple infections varied significantly across age groups(P<0.001).Conclusion:The HR-HPV infection rate among women undergoing health examinations in Xinjiang has declined yearly,with the predominant subtypes being types 16,52,and 58,and single infections being the most common.关键词
高危型人乳头瘤病毒(HR-HPV)/门诊/健康体检/多重感染Key words
High-risk human papillomavirus(HR-HPV)/Outpatient department/Health check-up/Multiple infections分类
临床医学引用本文复制引用
朱开春,韩莉莉,王琳,陆萍,郭敏,孙美凤,王新颜,玛依努尔·尼牙孜..2014至2021年新疆地区妇女高危型HPV感染特点及趋势分析[J].现代妇产科进展,2025,34(6):425-428,436,5.基金项目
新疆维吾尔自治区自然科学基金项目(No:2022D01C103) （No:2022D01C103）
新疆维吾尔自治区青年科技拔尖人才专项(No:2022TSYCCX0110) （No:2022TSYCCX0110）
