现代医药卫生2025，Vol.41Issue(6)：1323-1326,4.DOI:10.3969/j.issn.1009-5519.2025.06.007
腰围与女性乳腺癌发病风险的相关性研究
Correlation between waist circumference and risk of breast cancer in women
摘要
Abstract
Objective To explore the correlation between waist circumference and the risk of breast cancer in women.Methods A total of 620 female subjects were included in the study from the NHANES da-tabase from 2005 to 2014.They were divided into breast cancer group and non-breast cancer group according to whether they had breast cancer,with 310 cases in each group.The general data of the two groups were com-pared,and the correlation between waist circumference and the risk of female breast cancer was analyzed.Re-sults There were significant differences in age,education level,waist circumference,triglycerides,fasting blood glucose,glycosylated hemoglobin,estimated glomerular filtration rate,comorbid diabetes mellitus and comorbid hypertension between the two groups(P<0.05).There were no significant differences in income poverty rate,body mass index,body weight,total cholesterol,high-density cholesterol,smoking history,drink-ing history and concomitant stroke between the two groups(P>0.05).Unadjusted logistic regression analysis(only waist circumference analysis)showed that waist circumference was significantly associated with the risk of breast cancer(OR=1.18,95%CI 1.06-1.31,P=0.002).After adjusting BMI,age,smoking history and drinking history,waist circumference was still significantly associated with the risk of breast cancer.Every 10cm increase in waist circumference,the risk of breast cancer increased by 27%(OR=1.27,95%CI 1.01-1.60,P=0.038).The results of restricted cubic spline analysis showed that the risk of breast cancer increased with the increase of waist circumference.Conclusion Waist circumference is an independent risk factor for breast cancer in women.The increase of waist circumference can increase the risk of breast cancer.关键词
乳腺癌/腰围/肥胖/身体质量指数Key words
Breast cancer/Waist circumference/Obesity/Body mass index分类
医药卫生引用本文复制引用
贺叶,冯翠群,王建国..腰围与女性乳腺癌发病风险的相关性研究[J].现代医药卫生,2025,41(6):1323-1326,4.基金项目
湖南省卫生健康委员会科研项目(B202314028514) （B202314028514）
湖南省湘潭市医学科研项目(2022-xtyx-27). （2022-xtyx-27）
